a Department of Medicine and Bioregulatory Science , Graduate School of Medical Sciences, Kyushu University , Fukuoka , Japan.
b Digestive Diseases Branch , NIDDK, NIH , Bethesda , MD , USA.
Expert Rev Anticancer Ther. 2018 Sep;18(9):837-860. doi: 10.1080/14737140.2018.1496822. Epub 2018 Jul 17.
Recently, there have been a number of advances in imaging pancreatic neuroendocrine tumors (panNETs), as well as other neuroendocrine tumors (NETs), which have had a profound effect on the management and treatment of these patients, but in some cases are also associated with controversies. Areas covered: These advances are the result of numerous studies attempting to better define the roles of both cross-sectional imaging, endoscopic ultrasound, with or without fine-needle aspiration, and molecular imaging in both sporadic and inherited panNET syndromes; the increased attempt to develop imaging parameters that correlate with tumor classification or have prognostic value; the rapidly increasing use of molecular imaging in these tumors and the attempt to develop imaging parameters that correlate with treatment/outcome results. Each of these areas and the associated controversies are reviewed. Expert commentary: There have been numerous advances in all aspects of the imaging of panNETs, as well as other NETs, in the last few years. The advances are leading to expanded roles of imaging in the management of these patients and the results being seen in panNETs/GI-NETs with these newer techniques are already being used in more common tumors.
近年来，在胰腺神经内分泌肿瘤（panNETs）以及其他神经内分泌肿瘤（NETs）的成像方面取得了许多进展，这些进展对这些患者的管理和治疗产生了深远的影响，但在某些情况下也存在争议。涵盖领域：这些进展是众多研究的结果，这些研究试图更好地定义横断面成像、内镜超声（伴或不伴细针抽吸）以及分子成像在散发性和遗传性 panNET 综合征中的作用；越来越多地尝试开发与肿瘤分类相关或具有预后价值的成像参数；这些肿瘤中分子成像的快速应用以及尝试开发与治疗/结果相关的成像参数。审查了这些领域及其相关争议。专家评论：在过去几年中，panNETs 以及其他 NETs 的成像在各个方面都取得了许多进展。这些进展导致了成像在这些患者管理中的作用扩大，并且在这些新技术中观察到的 panNETs/GI-NETs 的结果已经在更常见的肿瘤中得到应用。
