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母亲焦虑倾向与妊娠结局是否存在关联?

Is there an association between maternal anxiety propensity and pregnancy outcomes?

机构信息

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Helen Schneider Hospital for Women, Rabin Medical Center, 49100, Petach-Tikva, Israel.

出版信息

BMC Pregnancy Childbirth. 2018 Jul 4;18(1):287. doi: 10.1186/s12884-018-1925-8.

Abstract

BACKGROUND

Several studies have shown inconsistent associations between anxiety during pregnancy and adverse pregnancy outcome. This inconsistency may be due to lack of controlling for the timing and type of maternal anxiety. We aimed to isolate a specific type of anxiety - maternal anxiety propensity, which is not directly related to pregnancy, and evaluate its association with adverse pregnancy outcome.

METHODS

We conducted a prospective observational study of 512 pregnant women, followed to delivery. The trait anxiety scale of the State-Trait Anxiety Inventories was used in order to detect a propensity towards anxiety. The association between anxiety propensity (defined as trait-anxiety subscale score above 38) and adverse pregnancy outcome was evaluated. Primary outcome was a composite outcome including preterm birth prior to 37 gestational weeks, hypertensive disorders in pregnancy, small for gestational age newborn and gestational diabetes mellitus. Secondary outcomes were each one of the above mentioned gestational complications.

RESULTS

There were no significant between-group differences in adverse pregnancy outcomes, including the rate of preterm birth, hypertensive disorders, small for gestational age, gestational diabetes or a composite outcome of them all.

CONCLUSION

Anxiety propensity is not associated with adverse pregnancy outcome.

摘要

背景

多项研究表明,孕妇焦虑与不良妊娠结局之间的关联并不一致。这种不一致可能是由于缺乏对母体焦虑的时间和类型的控制。我们旨在分离一种特定类型的焦虑 - 母体焦虑倾向,这种焦虑与妊娠没有直接关系,并评估其与不良妊娠结局的关联。

方法

我们进行了一项前瞻性观察研究,纳入了 512 名孕妇,随访至分娩。采用状态-特质焦虑量表检测焦虑倾向。评估焦虑倾向(特质焦虑分量表得分高于 38 分)与不良妊娠结局之间的关联。主要结局是包括 37 孕周前早产、妊娠高血压疾病、小于胎龄儿和妊娠期糖尿病在内的复合结局。次要结局是上述每一种妊娠并发症。

结果

两组在不良妊娠结局(包括早产、高血压疾病、小于胎龄儿、妊娠期糖尿病或它们的复合结局)发生率方面无显著差异。

结论

焦虑倾向与不良妊娠结局无关。

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