Huffman Amanda L, Bromberg Julie E, Augustson Erik M
Am J Health Behav. 2018 Jul 1;42(4):90-101. doi: 10.5993/AJHB.42.4.9.
Objectives In this study, we attempt to elucidate the relationship between lifetime mental illness (LMI), particularly a depression diagnosis, and smoking cessation. Methods Data were drawn from a previous study and include LMI, demographics, mood, and smoking cessation outcomes. We evaluated the relationship between multiple LMIs and smoking cessation at 7 months post-intervention, and depression in combination with another LMI. Results At 7 months, the adjusted odds of cessation for those with one LMI, including depression, were 0.74 (p = .102), and for those with 2+ LMIs, 0.69 (p = .037), both in comparison with participants who reported no history of LMI. Among those with 2+ LMIs, the adjusted odds of cessation for those with a depression diagnosis were 0.34 (p = .007) compared to those whose multiple LMIs did not include depression. Conclusions Among smokers seeking cessation treatment, those who had 2+ LMIs were at greater risk of relapse, an effect particularly marked in smokers with depression. This study adds to the literature examining the potential impact of LMI on smokers' ability to quit by considering the potential impact of 2+ LMIs and highlights the potential impact of depression as a risk factor for continued smoking.
目的 在本研究中，我们试图阐明终生精神疾病（LMI），尤其是抑郁症诊断与戒烟之间的关系。方法 数据取自先前的一项研究，包括LMI、人口统计学、情绪和戒烟结果。我们评估了多种LMI与干预后7个月戒烟之间的关系，以及抑郁症与另一种LMI合并存在时的关系。结果 在7个月时，与报告无LMI病史的参与者相比，患有包括抑郁症在内的一种LMI的参与者的校正戒烟几率为0.74（p = 0.102），患有两种或更多LMI的参与者的校正戒烟几率为0.69（p = 0.037）。在患有两种或更多LMI的参与者中，与多种LMI不包括抑郁症的参与者相比，被诊断为抑郁症的参与者的校正戒烟几率为0.34（p = 0.007）。结论 在寻求戒烟治疗的吸烟者中，患有两种或更多LMI的吸烟者复发风险更高，这种影响在患有抑郁症的吸烟者中尤为明显。本研究通过考虑两种或更多LMI的潜在影响，为研究LMI对吸烟者戒烟能力的潜在影响增添了文献，并强调了抑郁症作为持续吸烟风险因素的潜在影响。
