Di Iorio Walter, Ciarimboli Alessandro, Ferriero Giorgio, Feleppa Michele, Baratto Luigi, Matarazzo Giuseppe, Gentile Giovanni, Masiero Stefano, Sale Patrizio
Rehabilitation Unit, Villa Margherita, 82100 Benevento, Italy.
Division of Physical Medicine and Rehabilitation, Salvatore Maugeri Foundation, Scientific Institute of Lissone, IRCCS, 20851 Lissone, Italy.
Diseases. 2018 Jul 4;6(3):58. doi: 10.3390/diseases6030058.
The aim of this study was to assess the role of Action Observation (AO) to improve balance, gait, reduce falls, and to investigate the changes in P300 pattern. Five cognitively intact People with Parkinson’s disease (PwP) were enrolled in this prospective, quasi-experimental study to undergo a rehabilitation program of AO for gait and balance recovery of 60 min, three times a week for four weeks. The statistical analysis showed significant improvements for Unified Parkinson’s Disease Rating Scale (UPDRS) motor section III = 0.0082, Short form 12-items Healthy Survey (SF-12) Mental Composite Score (MCS) = 0.0007, Freezing of gait Questionnaire (FOG-Q) = 0.0030, The 39-items Parkinson’s Disease Questionnaire (PDQ-39) = 0.100, and for P300ld = 0.0077. In conclusion, AO reveals to be a safe and feasible paradigm of rehabilitative exercise in cognitively preserved PwP.
本研究的目的是评估动作观察（AO）在改善平衡、步态、减少跌倒方面的作用，并研究P300模式的变化。五名认知功能完好的帕金森病患者（PwP）参与了这项前瞻性、准实验性研究，接受为期四周、每周三次、每次60分钟的AO康复计划，以恢复步态和平衡。统计分析显示，统一帕金森病评定量表（UPDRS）运动部分III（P = 0.0082）、简短健康调查问卷12项版（SF - 12）心理综合评分（MCS）（P = 0.0007）、步态冻结问卷（FOG - Q）（P = 0.0030）、39项帕金森病问卷（PDQ - 39）（P = 0.100）以及P300潜伏期（P = 0.0077）均有显著改善。总之，在认知功能保留的PwP中，AO是一种安全可行的康复锻炼模式。
