Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong.
School of Science and Health, Western Sydney University, Penrith, NSW, Australia.
Neural Plast. 2018 Apr 24;2018:2321045. doi: 10.1155/2018/2321045. eCollection 2018.
To evaluate the concurrent and training effects of action observation (AO) and action execution with mirror visual feedback (MVF) on the activation of the mirror neuron system (MNS) and its relationship with the activation of the motor cortex in stroke individuals.
A literature search using CINAHL, PubMed, PsycINFO, Medline, Web of Science, and SCOPUS to find relevant studies was performed.
A total of 19 articles were included. Two functional magnetic resonance imaging (fMRI) studies reported that MVF could activate the ipsilesional primary motor cortex as well as the MNS in stroke individuals, whereas two other fMRI studies found that the MNS was not activated by MVF in stroke individuals. Two clinical trials reported that long-term action execution with MVF induced a shift of activation toward the ipsilesional hemisphere. Five fMRI studies showed that AO activated the MNS, of which, three found the activation of movement-related areas. Five electroencephalography (EEG) studies demonstrated that AO or MVF enhanced mu suppression over the sensorimotor cortex.
MVF may contribute to stroke recovery by revising the interhemispheric imbalance caused by stroke due to the activation of the MNS. AO may also promote motor relearning in stroke individuals by activating the MNS and motor cortex.
评估动作观察（AO）与镜像视觉反馈（MVF）的同时性和训练效果对脑卒中个体的镜像神经元系统（MNS）的激活及其与运动皮层激活之间的关系。
使用 CINAHL、PubMed、PsycINFO、Medline、Web of Science 和 SCOPUS 进行文献检索，以查找相关研究。
共纳入 19 篇文章。两项功能磁共振成像（fMRI）研究报告称，MVF 可激活脑卒中个体的对侧初级运动皮层和 MNS，而另外两项 fMRI 研究则发现 MVF 不能激活脑卒中个体的 MNS。两项临床试验报告称，长期进行 MVF 动作执行可引起激活向对侧半球转移。五项 fMRI 研究表明 AO 可激活 MNS，其中三项研究发现了与运动相关区域的激活。五项脑电图（EEG）研究表明，AO 或 MVF 可增强感觉运动皮层上的 mu 抑制。
MVF 通过激活 MNS 来纠正脑卒中引起的大脑半球间失衡，从而有助于脑卒中康复。AO 也可能通过激活 MNS 和运动皮层来促进脑卒中个体的运动再学习。
