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机器人辅助腹膜后腹腔镜手术及术前RENAL评分在肾肿瘤患者保留肾单位手术中的临床应用评估

Evaluation of the Clinical Use of Robot-Assisted Retroperitoneal Laparoscopy and Preoperative RENAL Scoring for Nephron Sparing Surgery in Renal Tumor Patients.

作者信息

Xia Yu, Wang Gong-Xian, Fu Bin, Liu Wei-Peng, Zhang Cheng, Zhou Xiao-Chen

机构信息

Department of Urology, The First Affiliated Hospital Of Nanchang University, Nanchang, Jiangxi China.

出版信息

Indian J Surg. 2018 Jun;80(3):252-258. doi: 10.1007/s12262-016-1572-0. Epub 2016 Dec 26.

Abstract

The present study aims to compare the operative outcomes following the use of robot-assisted retroperitoneal partial nephrectomy (RARPN) with radius, exophytic/endophytic, nearness to sinus, anterior/posterior, and location (RENAL) scoring or laparoscopic retroperitoneal partial nephrectomy (LRPN) for the treatment of renal tumors. Eighty-three nephron-sparing surgery (NSS) procedures performed between January 2013 and December 2015 were reviewed. The study set consisted of 26 robot-assisted retroperitoneal laparoscopes, of which 3 were high risk (RENAL score ≥10), 11 were medium risk (RENAL score ≥7 < 9), and 12 were low risk (RENAL score <7) and 57 laparoscopic retroperitoneal partial nephrectomy procedures (7 high, 22 medium, and 28 low risk). All surgeries were successful in the absence of conversion or transfusion. Operative times were 96.0 ± 16.9 and 110.0 ± 19.4 min for RARPN and LRPN, respectively ( < 0.05). Warm ischemia times (WITs) were 17.6 ± 3.1 and 22.8 ± 3.5 min, respectively ( < 0.05). Estimated blood losses (EBLs) were 45 ± 15 and 97 ± 25 mL, respectively ( < 0.05). No statistical significance was found in duration of drainage, intestinal recovery time, hospital stay, serum creatinine, and perioperative complications ( > 0.05). RARPN affords significant advantages in outcomes of WIT, EBL, and recovery time over conventional LRPN owing to an increased accuracy in excision and suturing. Patients bearing high-risk renal tumors (RENAL score ≥10) are suitable candidates for RARPN.

摘要

本研究旨在比较机器人辅助腹膜后肾部分切除术(RARPN)与采用半径、外生性/内生性、靠近肾窦程度、前后位及位置(RENAL)评分法或腹腔镜腹膜后肾部分切除术(LRPN)治疗肾肿瘤后的手术效果。回顾了2013年1月至2015年12月期间进行的83例保留肾单位手术(NSS)。研究组包括26例机器人辅助腹膜后腹腔镜手术,其中3例为高风险(RENAL评分≥10),11例为中度风险(RENAL评分≥7且<9),12例为低风险(RENAL评分<7),以及57例腹腔镜腹膜后肾部分切除术(7例高风险、22例中度风险和28例低风险)。所有手术均成功完成,未出现中转或输血情况。RARPN和LRPN的手术时间分别为96.0±16.9分钟和110.0±19.4分钟(P<0.05)。热缺血时间(WIT)分别为17.6±3.1分钟和22.8±3.5分钟(P<0.05)。估计失血量(EBL)分别为45±15毫升和97±25毫升(P<0.05)。引流时间、肠道恢复时间、住院时间、血清肌酐及围手术期并发症方面未发现统计学差异(P>0.05)。由于切除和缝合的准确性提高,RARPN在WIT、EBL和恢复时间方面比传统LRPN具有显著优势。患有高风险肾肿瘤(RENAL评分≥10)的患者是RARPN的合适候选者。

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Tumor complexity predicts malignant disease for small renal masses.肿瘤复杂性可预测小肾肿瘤的恶性疾病。
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