Biostatistics/Epidemiology/Research Design (BERD) Core, Center for Clinical and Translational Sciences (CCTS), University of Texas Health Science Center at Houston, 6410 Fannin St, Suite 1100, Houston, TX, 77030, USA.
Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Ste 1402, Boston, MA, 02115, USA.
J Autism Dev Disord. 2020 Apr;50(4):1411-1417. doi: 10.1007/s10803-018-3676-9.
Previous studies have implicated migration and ethnicity as possible risk factors for autism spectrum disorder (ASD) in developed countries. Using Texas education data, we calculated district-reported ASD prevalence stratified by geographic region, with reported home language as a proxy for immigration. Prevalence ratios were also stratified by race. Prevalence estimates were significantly lower for White children from homes speaking Spanish and other non-English languages compared to those from English-speaking homes. This is the first study, to our knowledge, that investigates ASD prevalence of children from non-English-speaking households in a large sample. Barriers in identification of children of immigrants with ASD indicate that the increased district-reported prevalence seen in our study may only be a small indicator of a potentially larger prevalence.
先前的研究表明，在发达国家，迁移和种族可能是自闭症谱系障碍（ASD）的潜在风险因素。我们使用德克萨斯州的教育数据，按地理区域对地区报告的 ASD 患病率进行分层，以报告的家庭语言作为移民的替代指标。我们还按种族对患病率比进行分层。与来自讲英语家庭的孩子相比，来自讲西班牙语和其他非英语语言家庭的白人孩子的患病率明显较低。据我们所知，这是第一项在大样本中调查非英语家庭儿童 ASD 患病率的研究。识别移民儿童 ASD 方面的障碍表明，我们的研究中观察到的地区报告患病率增加可能只是潜在更大患病率的一个小指标。
