Patel Jilen, Anthonappa Robert P, King Nigel M
UWA Dental School, The University of Western Australia, Nedlands, WA, Australia.
Int J Paediatr Dent. 2018 Jul 4. doi: 10.1111/ipd.12401.
Silver diamine fluoride (SDF) is a cariostatic agent used to adjunctively manage dental caries in high-risk groups. However, black staining is a frequently reported side effect following SDF application and influences the acceptability of this treatment.
To evaluate the staining potential of SDF and the influence of the potassium Iodide (KI) application on the degree of black staining over time.
Extracted carious primary molars were collected and sorted into pairs matched by tooth type, size and location of the carious lesion (n = 35). Teeth were stratified to receive either 38% SDF, KI immediately after SDF application, or 12% SDF. Standardised timelapse photography and image processing software was used to evaluate staining over a period of 7 days.
Following SDF application, the onset of black staining occurred within 2 min and increased in value for up to 6 h post-application. The use of KI immediately after SDF application resulted in no noticeable staining of the carious dentine or surrounding enamel. No significant differences were evident in the staining potential between the different SDF concentrations (38% and 12%). Furthermore, root surface and cementum was found to stain darker and more readily when compared with the coronal enamel surface.
SDF has the ability to visibly stain dental hard tissues and its staining potential may be modified by application of KI.
氟化亚锡（SDF）是一种用于辅助管理高危人群龋齿的抑龋剂。然而，黑色染色是SDF应用后经常报道的副作用，会影响这种治疗方法的可接受性。
评估SDF的染色潜力以及碘化钾（KI）应用对黑色染色程度随时间的影响。
收集拔除的龋损乳牙，按牙齿类型、大小和龋损部位配对分类（n = 35）。牙齿分层接受38% SDF、SDF应用后立即应用KI或12% SDF。使用标准化的延时摄影和图像处理软件评估7天内的染色情况。
应用SDF后，黑色染色在2分钟内出现，并在应用后6小时内颜色值增加。SDF应用后立即使用KI，龋损牙本质或周围釉质未出现明显染色。不同SDF浓度（38%和12%）之间的染色潜力无明显差异。此外，与冠部釉质表面相比，根面和牙骨质染色更深且更容易。
SDF能够明显使牙齿硬组织染色，其染色潜力可通过应用KI进行改变。
