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评价 Silver Diamine Fluoride、Potassium Iodide、Nanosilver Fluoride 的染色潜力:一项体外研究。

Evaluation of staining potential of Silver Diamine Fluoride, Potassium Iodide, Nanosilver Fluoride: an in vitro study.

机构信息

Department of Pediatric Dentistry, Faculty of Dentistry, Istanbul University, İstanbul, Türkiye.

Department of Chemical Engineering, Faculty of Engineering, Istanbul University-Cerrahpaşa, İstanbul, Türkiye.

出版信息

BMC Oral Health. 2024 Jun 16;24(1):699. doi: 10.1186/s12903-024-04370-y.

DOI:10.1186/s12903-024-04370-y
PMID:38880907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11180397/
Abstract

BACKGROUND

The black staining effect of silver-containing solutions for use to arrest caries can have a negative aesthetic impact on children and parents. This study aims to assess the staining effects of Silver Diamine Fluoride/Potassium Iodide (SDF/KI), SDF and Nanosilver Fluoride (NSF).

MATERIALS AND METHODS

Forty-four extracted carious primary molars were collected and randomly divided into four groups (n = 11). The carious tissue in all teeth was removed using a chemo-mechanical caries removal agent with an excavator. After caries removal in all groups, SDF, SDF/KI, and NSF were applied to the different groups, while no solution was applied to the control group. Subsequently, the teeth in all groups were restored with compomer. Color values L*, a* and b* were measured using a spectrophotometer at three time points: immediately after compomer restoration (T), one week later (T), and four week later (T). Changes in brightness (ΔL) and color (ΔE) over time were calculated and comparisons among groups were made.

RESULTS

The SDF solution induced statistically significant black staining (p = 0.013) and a decrease in L* value (p < 0.001) on the compomer material compared to the other groups over time.

CONCLUSIONS

It was observed that SDF/KI has the potential to reduce the black staining effect of SDF, though not entirely. Novel experimental solutions like NSF may offer an alternative to counteract the staining effect of SDF.

摘要

背景

含银溶液用于控制龋齿的黑色染色效果可能会对儿童和家长的美观产生负面影响。本研究旨在评估 Silver Diamine Fluoride/Potassium Iodide(SDF/KI)、SDF 和 Nanosilver Fluoride(NSF)的染色效果。

材料和方法

收集 44 颗已拔除的龋坏乳磨牙并将其随机分为四组(n=11)。所有牙齿的龋坏组织均使用带有牙钻的化学机械去龋剂去除。在所有组去龋完成后,将 SDF、SDF/KI 和 NSF 分别应用于不同的组,而对照组则不应用任何溶液。随后,所有组的牙齿均用复合树脂修复。使用分光光度计在三个时间点测量 L*、a和 b颜色值:复合树脂修复后即刻(T)、一周后(T)和四周后(T)。计算随时间的亮度变化(ΔL)和颜色变化(ΔE),并对组间进行比较。

结果

与其他组相比,SDF 溶液在复合树脂材料上随时间推移产生了统计学上显著的黑色染色(p=0.013)和 L*值降低(p<0.001)。

结论

观察到 SDF/KI 有可能降低 SDF 的黑色染色效果,但并非完全如此。像 NSF 这样的新型实验溶液可能是对抗 SDF 染色效果的替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/0e8ede0c86ee/12903_2024_4370_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/964c50c71323/12903_2024_4370_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/083878a070ac/12903_2024_4370_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/79c4e2e76afe/12903_2024_4370_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/0e8ede0c86ee/12903_2024_4370_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/964c50c71323/12903_2024_4370_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/083878a070ac/12903_2024_4370_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/79c4e2e76afe/12903_2024_4370_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42dc/11180397/0e8ede0c86ee/12903_2024_4370_Fig4_HTML.jpg

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Antibiotics (Basel). 2023 Feb 2;12(2):298. doi: 10.3390/antibiotics12020298.
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Potential discolouration of silver diamine fluoride versus silver diamine fluoride/potassium iodide in primary teeth: a randomised clinical study.乳牙中氟化亚银与氟化亚银/碘化钾的潜在变色情况:一项随机临床研究。
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