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古细菌沃氏甲烷球菌中包含高表达基因的转录单元的终止

Termination of a transcription unit comprising highly expressed genes in the archaebacterium Methanococcus voltae.

作者信息

Müller B, Allmansberger R, Klein A

出版信息

Nucleic Acids Res. 1985 Sep 25;13(18):6439-45. doi: 10.1093/nar/13.18.6439.

Abstract

The 3'termini of transcripts originating from genes organized in a highly expressed transcription unit were analyzed in the archaebacterium Methanococcus voltae. The putative termination signals were found in an AT-rich intergenic region following the 3'-terminal gene. The two detected signals both contain oligo(T) sequences. A possible stem/loop structure immediately precedes one of the oligo(T) tracts. This secondary structure is considered to have an additional function in stabilizing the transcripts.

摘要

对源自高度表达转录单元中基因的转录本的3'末端,在古细菌沃氏甲烷球菌中进行了分析。推定的终止信号位于3'末端基因之后富含AT的基因间隔区。检测到的两个信号均含有寡聚(T)序列。在其中一个寡聚(T)序列之前紧挨着一个可能的茎环结构。这种二级结构被认为在稳定转录本方面具有额外功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e9b/321969/a668a097fe59/nar00312-0051-a.jpg

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