液体活检中的循环肿瘤DNA和循环肿瘤细胞——现状与未来发展方向
ctDNA and CTCs in Liquid Biopsy - Current Status and Where We Need to Progress.
作者信息
Neumann Martin H D, Bender Sebastian, Krahn Thomas, Schlange Thomas
机构信息
Bayer AG, Pharmaceutical Division, Biomarker Research, Wuppertal, Germany.
Bayer AG, Pharmaceutical Division, Translational Assay Technology, Berlin, Germany.
出版信息
Comput Struct Biotechnol J. 2018 Jun 1;16:190-195. doi: 10.1016/j.csbj.2018.05.002. eCollection 2018.
Abstract
We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview of corresponding technologies is given.
摘要
我们讨论了液体活检的现状及其优势与挑战，重点关注分析前样本处理、技术和工作流程。指出了循环肿瘤细胞和循环肿瘤DNA的潜力，并对相应技术进行了概述。
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