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一名儿科患者的胡芦巴过敏反应

Fenugreek Anaphylaxis in a Pediatric Patient.

作者信息

Joseph Nancy I, Slavin Eileen, Peppers Brian P, Hostoffer Robert W

机构信息

Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA.

出版信息

Allergy Rhinol (Providence). 2018 Apr 12;9:2152656718764134. doi: 10.1177/2152656718764134. eCollection 2018 Jan-Dec.

DOI:10.1177/2152656718764134
PMID:29977649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6028160/
Abstract

Fenugreek ( is a food product that belongs to the family along with other legumes. It has been used in India, Greece, and Egypt for culinary and medical purposes since ancient times, and today, fenugreek is used for flavoring foods, dyes, and drugs throughout the world. Many members of the family have been associated with allergies including soybean, green pea, and peanut. Fenugreek is also included in this family and may result in allergic reactions. Two cases of anaphylaxis have been described in children after ingestion of curry and pastes that contain fenugreek, although the true nature of the causative agent was unclear. We report the first case of fenugreek anaphylaxis in a pediatric patient defined by skin testing, immunoglobulin E ImmunoCAP assays, and clear ingestion.

摘要

葫芦巴是一种食品,与其他豆类同属豆科。自古以来,它在印度、希腊和埃及就被用于烹饪和医疗目的,如今,葫芦巴在世界各地被用于食品调味、染色和制药。豆科的许多成员都与过敏有关,包括大豆、青豆和花生。葫芦巴也属于这个科,可能会导致过敏反应。有两例儿童在摄入含有葫芦巴的咖喱和糊状物后发生过敏反应的病例报道,尽管致病因素的真正性质尚不清楚。我们报告了第一例通过皮肤试验、免疫球蛋白E免疫捕获分析以及明确的摄入史确诊的儿科患者葫芦巴过敏病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/621e/6028160/b7a8ed5e63a2/10.1177_2152656718764134-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/621e/6028160/b7a8ed5e63a2/10.1177_2152656718764134-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/621e/6028160/b7a8ed5e63a2/10.1177_2152656718764134-fig1.jpg

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本文引用的文献

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Cross-allergic reactions to legumes in lupin and fenugreek-sensitized mice.豆类过敏的小鼠对羽扇豆和胡芦巴的交叉过敏反应。
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Anaphylactic reactions in mice with Fenugreek allergy.对葎草过敏的小鼠的过敏反应。
Scand J Immunol. 2011 Oct;74(4):342-53. doi: 10.1111/j.1365-3083.2011.02587.x.
5
Characterization of potential allergens in fenugreek (Trigonella foenum-graecum) using patient sera and MS-based proteomic analysis.利用患者血清和基于 MS 的蛋白质组学分析鉴定胡芦巴(Trigonella foenum-graecum)中的潜在过敏原。
J Proteomics. 2010 May 7;73(7):1321-33. doi: 10.1016/j.jprot.2010.02.011. Epub 2010 Feb 26.
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Food allergy.食物过敏。
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Allergenicity and antigenicity of fenugreek (Trigonella foenum-graecum) proteins in foods.食品中胡芦巴(Trigonella foenum-graecum)蛋白质的变应原性和抗原性。
J Allergy Clin Immunol. 2009 Jan;123(1):187-94. doi: 10.1016/j.jaci.2008.09.012. Epub 2008 Oct 19.
8
Allergy to fenugreek (Trigonella foenum graecum).对胡芦巴(Trigonella foenum graecum)过敏。
Ann Allergy Asthma Immunol. 1997 Mar;78(3):297-300. doi: 10.1016/S1081-1206(10)63185-7.