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脊髓性肌萎缩症患儿的振动辅助家庭训练计划

Vibration-Assisted Home Training Program for Children With Spinal Muscular Atrophy.

作者信息

Stark Christina, Duran Ibrahim, Cirak Sebahattin, Hamacher Stefanie, Hoyer-Kuhn Heike-Katharina, Semler Oliver, Schoenau Eckhard

机构信息

Children's and Adolescent's Hospital, University of Cologne, Cologne, Germany.

Cologne Center for Musculoskeletal Biomechanics (CCMB), University of Cologne, Cologne, Germany.

出版信息

Child Neurol Open. 2018 Jun 10;5:2329048X18780477. doi: 10.1177/2329048X18780477. eCollection 2018.

Abstract

The aim of this study was to determine the effect of a new method of vibration-assisted neuromuscular rehabilitation in patients with spinal muscular atrophy types II and III. In this retrospective observational study, 38 children (mean age: 4.64 ± 1.95 years) were analyzed. The physiotherapy program, , combines 6 months of home-based side-alternating whole-body vibration with interval blocks of intensive, goal-directed rehabilitation: 13 days at the start and 6 days after 3 months. Assessments were applied at the beginning (M0), after 6 months of home-based training (M6), and after 6 months of follow-up (M12). Motor abilities were assessed by the Gross Motor Function Measure 66 and Hammersmith Functional Mobility Scale. The Gross Motor Function Measure showed an increase of 1.69 (3.73) points ( = .124) and the Hammersmith Functional Mobility Scale a significant increase of 2.73 ± 1.79 points ( = .007) after 12 months; however, whether this leads to a long-term clinical benefit requires further investigation.

摘要

本研究的目的是确定一种新的振动辅助神经肌肉康复方法对Ⅱ型和Ⅲ型脊髓性肌萎缩症患者的影响。在这项回顾性观察研究中,对38名儿童(平均年龄:4.64±1.95岁)进行了分析。物理治疗方案将为期6个月的居家侧方交替全身振动与强化的、目标导向的康复间歇段相结合:开始时13天,3个月后6天。在开始时(M0)、居家训练6个月后(M6)和随访6个月后(M12)进行评估。通过粗大运动功能测量66和哈默史密斯功能活动量表评估运动能力。12个月后,粗大运动功能测量显示增加了1.69(3.73)分(P = 0.124),哈默史密斯功能活动量表显示显著增加了2.73±1.79分(P = 0.007);然而,这是否会带来长期临床益处还需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1d2/6024344/3d7d7228743c/10.1177_2329048X18780477-fig1.jpg

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