Stark Christina, Duran Ibrahim, Cirak Sebahattin, Hamacher Stefanie, Hoyer-Kuhn Heike-Katharina, Semler Oliver, Schoenau Eckhard
Children's and Adolescent's Hospital, University of Cologne, Cologne, Germany.
Cologne Center for Musculoskeletal Biomechanics (CCMB), University of Cologne, Cologne, Germany.
Child Neurol Open. 2018 Jun 10;5:2329048X18780477. doi: 10.1177/2329048X18780477. eCollection 2018.
The aim of this study was to determine the effect of a new method of vibration-assisted neuromuscular rehabilitation in patients with spinal muscular atrophy types II and III. In this retrospective observational study, 38 children (mean age: 4.64 ± 1.95 years) were analyzed. The physiotherapy program, , combines 6 months of home-based side-alternating whole-body vibration with interval blocks of intensive, goal-directed rehabilitation: 13 days at the start and 6 days after 3 months. Assessments were applied at the beginning (M0), after 6 months of home-based training (M6), and after 6 months of follow-up (M12). Motor abilities were assessed by the Gross Motor Function Measure 66 and Hammersmith Functional Mobility Scale. The Gross Motor Function Measure showed an increase of 1.69 (3.73) points ( = .124) and the Hammersmith Functional Mobility Scale a significant increase of 2.73 ± 1.79 points ( = .007) after 12 months; however, whether this leads to a long-term clinical benefit requires further investigation.
本研究的目的是确定一种新的振动辅助神经肌肉康复方法对Ⅱ型和Ⅲ型脊髓性肌萎缩症患者的影响。在这项回顾性观察研究中，对38名儿童（平均年龄：4.64±1.95岁）进行了分析。物理治疗方案将为期6个月的居家侧方交替全身振动与强化的、目标导向的康复间歇段相结合：开始时13天，3个月后6天。在开始时（M0）、居家训练6个月后（M6）和随访6个月后（M12）进行评估。通过粗大运动功能测量66和哈默史密斯功能活动量表评估运动能力。12个月后，粗大运动功能测量显示增加了1.69（3.73）分（P = 0.124），哈默史密斯功能活动量表显示显著增加了2.73±1.79分（P = 0.007）；然而，这是否会带来长期临床益处还需要进一步研究。
