Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Bioprocess Engineering Group, AlgaePARC, Wageningen University & Research, PO Box 16, 6700 AA, Wageningen, The Netherlands.
Microb Biotechnol. 2018 Sep;11(5):806-818. doi: 10.1111/1751-7915.13296. Epub 2018 Jul 5.
Microbes are ubiquitously distributed, and they are also present in algae production systems. The algal microbiome is a pivotal part of the alga holobiont and has a key role in modulating algal populations in nature. However, there is a lack of knowledge on the role of bacteria in artificial systems ranging from laboratory flasks to industrial ponds. Coexisting microorganisms, and predominantly bacteria, are often regarded as contaminants in algal research, but recent studies manifested that many algal symbionts not only promote algal growth but also offer advantages in downstream processing. Because of the high expectations for microalgae in a bio-based economy, better understanding of benefits and risks of algal-microbial associations is important for the algae industry. Reducing production cost may be through applying specific bacteria to enhance algae growth at large scale as well as through preventing the growth of a broad spectrum of algal pathogens. In this review, we highlight the latest studies of algae-microbial interactions and their underlying mechanisms, discuss advantages of large-scale algal-bacterial cocultivation and extend such knowledge to a broad range of biotechnological applications.
微生物广泛分布，也存在于藻类生产系统中。藻菌群是藻全生物群的关键部分，在调节自然界中藻类种群方面起着关键作用。然而，对于从实验室培养瓶到工业池塘等人工系统中细菌的作用，我们知之甚少。共存的微生物，主要是细菌，通常被视为藻类研究中的污染物，但最近的研究表明，许多藻类共生体不仅促进藻类生长，而且在下游加工中也具有优势。由于对生物基经济中微藻的高期望，更好地了解藻类-微生物的相互作用的好处和风险对于藻类产业很重要。降低生产成本可能是通过应用特定的细菌来促进藻类在大规模生产中的生长，以及通过防止广谱藻类病原体的生长。在这篇综述中，我们强调了最新的藻类-微生物相互作用及其潜在机制的研究，讨论了大规模藻类-细菌共培养的优势，并将这些知识扩展到广泛的生物技术应用中。
