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[子宫肌层细胞中钙离子水平的调节机制]

[Mechanisms of regulation of Ca2+ levels in myometrium cells].

作者信息

Kosterin S A, Kurskiĭ M D

出版信息

Ukr Biokhim Zh (1978). 1985 Sep-Oct;57(5):100-16.

PMID:2997960
Abstract

The ways and mechanisms of the Ca2+ concentration regulation in myometrium cells are analyzed. The plasma membrane is thoroughly studied for its role in the calcium control provision for the contractile activity of the uterus. The systems of Mg2+-ATP-dependent transport of Ca2+, sodium-calcium metabolism as well as regularities of the Ca2+ passive transfer in the sarcolemma vesicles are considered. The systems of the Mg2+-ATP- and N+-dependent transport of calcium are discussed for their contribution into regulation of calcium concentration in the myoplasm. Oxytocin and ions of bivalent metals (stimulators of the contractile activity of the uterus) are studied for their effect on the activity of the sarcolemma calcium pump.

摘要

分析了子宫肌层细胞中Ca2+浓度调节的方式和机制。深入研究了质膜在为子宫收缩活动提供钙控制方面的作用。考虑了Ca2+的Mg2+-ATP依赖性转运系统、钠钙代谢以及肌膜囊泡中Ca2+被动转运的规律。讨论了钙的Mg2+-ATP和N+依赖性转运系统对肌浆中钙浓度调节的贡献。研究了催产素和二价金属离子(子宫收缩活动的刺激剂)对肌膜钙泵活性的影响。

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