[催产素对子宫肌层肌膜钙泵的作用]
[Effect of oxytocin on the calcium pump in myometrium sarcolemma].
作者信息
Shinlova O P, Fomin V P, Kosterin S A
出版信息
Ukr Biokhim Zh (1978). 1987 Mar-Apr;59(2):75-9.
Oxytocin (10(-7) M) administered inside the myometrium sarcolemma vesicles closed outward by the cytoplasmic side is shown to inhibit Mg2+, ATP-dependent Ca2+ accumulation in these structures having no effect on the passive release of cation out of them. According to these results and to the data available in literature on the inhibitory action of the peptide hormone on Mg2+, Ca2+-ATPase of myometrium sarcolemma a conclusion is drawn that oxytocin inhibits the Ca pump activity in plasma membranes of the myometrium cells.
将10（-7）M的催产素注入子宫肌层肌膜囊泡内，该囊泡由细胞质侧向外封闭，结果表明，催产素可抑制这些结构中镁离子、ATP依赖的钙离子积累，而对阳离子从其中的被动释放没有影响。根据这些结果以及文献中关于肽类激素对子宫肌层肌膜镁离子、钙离子 - ATP酶抑制作用的现有数据，得出结论：催产素抑制子宫肌层细胞质膜中的钙泵活性。
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