Interdisciplinary Research centre in Biomedical Materials (IRCBM), COMSATS Institute of Information technology, Lahore, Pakistan.
Department of Computer Science, COMSATS Institute of Information technology, Lahore, Pakistan.
PLoS One. 2018 Jul 6;13(7):e0199978. doi: 10.1371/journal.pone.0199978. eCollection 2018.
The present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design portable colorimetric assays for acetone monitoring. The color of the paper sensor strip was observed to change from dark yellow to light yellowish in the presence of varying concentrations of acetone. Three different color analyzing models including RGB, HSV, and LAB were employed to probe the output optical signal, and their performance was compared in terms of better interpretation of the generated signal. The LAB model was found to provide better analytical figures of merit with a linear response for the acetone concentration ranging from 2.5 to 1500 ppm, and a limit of detection of 0.5 ppm. Furthermore, the specificity of the designed filter paper based sensor was demonstrated against different common interfering compounds. The results demonstrated the potential of our proposed filter paper based sensor as a novel tool for the analysis of acetone.
本工作旨在设计一种廉价、快速、便携且易于使用的滤纸条比色分析方法，用于定性和定量分析丙酮。将具有丙酮特异性光学信号探针的海藻酸钠凝胶负载到滤纸条表面，设计用于丙酮监测的便携式比色分析方法。在存在不同浓度的丙酮时，纸传感器条的颜色从深黄色变为浅黄色。采用三种不同的颜色分析模型，包括 RGB、HSV 和 LAB，来探测输出的光学信号，并比较它们在解释产生的信号方面的性能。结果表明，LAB 模型在检测丙酮浓度范围为 2.5 至 1500 ppm 时提供了更好的分析性能，检出限为 0.5 ppm。此外，还对设计的滤纸条基传感器对不同常见干扰化合物的特异性进行了验证。结果表明，我们提出的滤纸条基传感器具有作为分析丙酮的新型工具的潜力。
