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[从金樱子根中分离得到的一种新三萜酸]

[A new triterpenic acid from the roots of Rosa laevigata].

作者信息

Li Yu-lu, Dai Hua-nian, Ma Guo-xu, Zhang Wen, Wu Tong-yu, Wang Yun-qing, Zou Jie-ming, Zhong Xiao-qing, Zhou Yan-lin, Yuan Jing-quan, Xu Xu-dong, Yi Wei

出版信息

Yao Xue Xue Bao. 2017 Mar;52(3):425-9.

Abstract

This study was designed to investigate triterpenoids from the roots of Rosa laevigata Michx. The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa laevigata Michx. HPLC was used to analyze its purity and chemical constitution. Spectroscopy methods were used to determine their structures. Five constituents were isolated and identified as19α-OH-3β-E-feruloyl corosolic acid (1), 23-hydroxy-tormentic acid (2), 2α, 3β, 19α, 23- tetrahydroxy-12-en-28-oleanolic acid (3), 2α, 3α, 20β- trihydroxyurs-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (5). Compound 1 was assigned as a new compound, compounds 4, 5 were obtained from the genus Rosa for the first time.

摘要

本研究旨在研究金樱子根中的三萜类化合物。采用硅胶柱色谱法从金樱子根中分离化学成分。用高效液相色谱法分析其纯度和化学组成。采用光谱法确定其结构。分离并鉴定出5种成分,分别为19α-OH-3β-E-阿魏酰科罗索酸(1)、23-羟基 tormentic 酸(2)、2α,3β,19α,23-四羟基-12-烯-28-齐墩果酸(3)、2α,3α,20β-三羟基乌苏-13(18)-烯-28-酸(4)、2α,3β,20β-三羟基乌苏-13(18)-烯-28-酸(5)。化合物1被鉴定为新化合物,化合物4、5首次从蔷薇属植物中获得。

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