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比较 2017 年台湾血脂指南和西方高危患者血脂指南。

Comparison of the 2017 Taiwan lipid guidelines and the Western lipid guidelines for high risk patients.

机构信息

Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.

Departments of Internal Medicine and Medical Research, Mackay Memorial Hospital, Taipei, Taiwan, ROC; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan, ROC.

出版信息

J Chin Med Assoc. 2018 Oct;81(10):853-859. doi: 10.1016/j.jcma.2018.05.003. Epub 2018 Jul 3.

Abstract

Dyslipidemia is a major contributor in initiation, development and progression of atherosclerotic cardiovascular disease (ASCVD). Most lipid guidelines are from Europe and America and centered on the reduction of atherogenic lipids levels through lifestyle intervention and pharmacotherapy. Recently, the 2017 Taiwan lipid guidelines for high risk patients was published to facilitate the control of dyslipidemia in patients that are highly susceptible to ASCVD, including patients with preexisting ASCVD, diabetes, chronic kidney disease and familial hypercholesterolemia. Most recommendations outlined in the 2017 Taiwan lipid guidelines for high risk patients are in concordance with those of Western guidelines. However, based on evidence from the studies originating from Asia and local expert opinions, there are some recommendations different from the other guidelines. The purpose of the current review is to compare the similarities and differences between the perspectives of the 2017 Taiwan lipid guidelines for high risk patients and other Western guidelines in individuals at high risk of ASCVD. The definitions of high risk groups and treatment goals defined to achieve ASCVD risk reduction are specifically compared.

摘要

血脂异常是动脉粥样硬化性心血管疾病(ASCVD)发生、发展和进展的主要原因。大多数血脂指南来自欧洲和美国,其重点是通过生活方式干预和药物治疗来降低致动脉粥样硬化脂质水平。最近,发布了 2017 年台湾高危患者血脂指南,以帮助控制易患 ASCVD 的患者的血脂异常,包括已有 ASCVD、糖尿病、慢性肾脏病和家族性高胆固醇血症的患者。2017 年台湾高危患者血脂指南中列出的大多数建议与西方指南一致。然而,基于来自亚洲的研究和当地专家意见的证据,有一些建议与其他指南不同。本综述的目的是比较 2017 年台湾高危患者血脂指南与其他西方指南在 ASCVD 高危个体方面的相似点和不同点。特别比较了高危人群的定义和为降低 ASCVD 风险而设定的治疗目标。

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