Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium; Department of Biomedical Engineering, Wroclaw University of Science and Technology, Wroclaw, Poland; Department of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Department of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium; Department of Ophthalmology, Brussels University Hospital, Jette, Belgium.
Cont Lens Anterior Eye. 2019 Feb;42(1):70-74. doi: 10.1016/j.clae.2018.06.005. Epub 2018 Jul 3.
To quantify the effect of short-term miniscleral contact lens wear on the anterior eye surface of healthy eyes, including cornea, corneo-scleral junction and sclero-conjuctival area.
Twelve healthy subjects (29.9 ± 5.7 years) wore a highly gas-permeable miniscleral contact lens of 16.5 mm diameter during a 5-hour period. Corneo-scleral height profilometry was captured before, immediately following lens removal and 3 h after lens removal. Topography based corneo-scleral limbal radius estimates were derived from height measurements. In addition, elevation differences in corneal and scleral region were calculated with custom-written software. Sclero-conjuctival flattening within different sectors was analysed.
Short-term miniscleral lens wear significantly modifies the anterior eye surface. Significant limbal radius increment (mean ± standard deviation) of 146 ± 80 μm, (p = 0.004) and flattening of -122 ± 90 μm in the sclero-conjuctival area, (p << 0.001) were observed immediately following lens removal. These changes did not recede to baseline levels 3 h after lens removal. The greatest anterior eye surface flattening was observed in the superior sector. No statistically significant corneal shape change was observed immediately following lens removal or during the recovery period.
Short-term miniscleral contact lens wear in healthy eyes does not produce significant corneal shape changes measured with profilometry but alters sclero-conjuctival topography. In addition, sclero-conjuctival flattening was not uniformly distributed across the anterior eye.
定量评估短期巩膜接触镜佩戴对健康眼眼前节的影响，包括角膜、角巩膜缘和球结膜区域。
12 名健康受试者（29.9±5.7 岁）佩戴直径 16.5mm 的高度透气巩膜接触镜 5 小时。在佩戴前、取镜后即刻和取镜后 3 小时分别采集角巩膜高度轮廓测量值。通过高度测量值推导出基于地形图的角巩缘等效半径估计值。此外，还使用定制软件计算角膜和巩膜区域的高度差异。分析不同象限内球结膜的扁平化情况。
短期巩膜接触镜佩戴会显著改变眼前节。取镜后即刻观察到明显的角巩缘等效半径增加（平均值±标准差）146±80μm，（p=0.004）和球结膜区域的扁平化-122±90μm，（p<<0.001）。这些变化在取镜后 3 小时并未恢复到基线水平。在上方象限观察到最明显的眼前节扁平化。取镜后即刻或恢复期间均未观察到角膜形态的统计学显著变化。
健康眼短期巩膜接触镜佩戴不会导致角膜形态的明显变化，但会改变角巩膜和球结膜的形态。此外，球结膜的扁平化并不是均匀分布在前眼前节。
