Gallmeier E, Gress T M
Klinik für Innere Medizin, Gastroenterologie, Infektiologie, Endokrinologie und Stoffwechsel, Universitätsklinikum Giessen und Marburg GmbH, Baldinger Straße, 35043, Marburg, Deutschland.
Internist (Berl). 2018 Aug;59(8):805-822. doi: 10.1007/s00108-018-0460-z.
Pancreatic ductal adenocarcinoma represents the most common malignant tumor of the pancreas. Despite substantial research efforts and gradual diagnostic and therapeutic improvements, its prognosis remains dismal. In accordance with the current German, European, and US guidelines, this CME-article provides a comprehensive review of the disease. In addition, selected up-to-date aspects of epidemiology, etiopathology, genetics, and basic principles of diagnostics and therapy including potential future therapeutic options are discussed.
胰腺导管腺癌是胰腺最常见的恶性肿瘤。尽管进行了大量研究并在诊断和治疗方面逐步取得进展,但其预后仍然很差。根据当前德国、欧洲和美国的指南,这篇继续医学教育文章对该疾病进行了全面综述。此外,还讨论了流行病学、病因病理学、遗传学以及诊断和治疗的基本原则等最新选定方面,包括未来可能的治疗选择。