Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, 100193, People's Republic of China.
Arch Virol. 2018 Oct;163(10):2865-2869. doi: 10.1007/s00705-018-3932-5. Epub 2018 Jul 6.
Since early 2016, the Chinese goose industry has experienced severe outbreaks of gout; however, the etiological factor of the disease is still unclear. Here, we investigated the possible involvement of viral infection in the disease. Using sequence-independent PCR amplification, astrovirus sequences were generated from a gout case. Full-length genomic sequencing and sequence analysis of three goose astrovirus (GoAstV) strains revealed that they belong to a new avastrovirus most closely related to viruses classified within species Avastrovirus 3. The GoAstV was detected in 16/16 gout cases collected from two provinces, supporting a pathogenic role for the new avastrovirus.
自 2016 年初以来，中国鹅产业经历了严重的痛风暴发；然而，该病的病因仍不清楚。在这里，我们研究了病毒感染在疾病中的可能作用。通过无序列依赖性 PCR 扩增，从痛风病例中产生了星状病毒序列。三种鹅星状病毒（GoAstV）株的全长基因组测序和序列分析表明，它们属于一种新的星状病毒，与分类为星状病毒 3 种的病毒最为密切相关。在从两个省份收集的 16/16 例痛风病例中检测到了 GoAstV，支持新的星状病毒具有致病性。
