Nursing College of Anhui Medical University, Feicui Road, Jingkai District, Hefei, 230032, Anhui Province, People's Republic of China.
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Arch Womens Ment Health. 2019 Apr;22(2):279-287. doi: 10.1007/s00737-018-0885-3. Epub 2018 Jul 6.
Postpartum depression is a common complication of childbearing and up to 12 months postpartum. This study aimed to determine the prevalence of postpartum depressive mood (PDM) in China by performing a meta-analysis of published studies. Studies that reported the prevalence of PDM in China were identified by searching the PubMed, Embase, CNKI, and CQVIP databases. Three thousand, one hundred, and two articles were obtained, and after careful evaluation, 26 studies were finally included in the meta-analysis. The combined studies included a total of 7618 cases with 1621 cases of PDM. The studies were assessed on the basis of heterogeneity testing and the potential for publication bias. Stata software 11.0 was used to perform the meta-analysis. The random-effect model showed that the prevalence of PDM was 21% with a 95% confidence interval (CI) of 17-25%. PDM was the highest 0 to 1.5 months after delivery. PDM levels decreased to 10.4% (95% CI 9.7-11.1%, P < 0.001) after publication bias were corrected. Sensitivity analyses evaluated the stability of our results and showed no significant change when any single study was excluded. Subgroup analyses showed that region, instruments used, cut-off score, and time points for depression assessment were positively associated with PDM prevalence. The prevalence of PDM differed among regions, with South Central China and East China exhibiting the lowest prevalence. The prevalence was higher in regions with poor economic development, suggesting that more attention should be devoted to Southwest and North China and that the prevalence of PDM should be evaluated 0 to 1.5 months after delivery.
产后抑郁症是生育期的常见并发症,可发生于产后 12 个月内。本研究旨在通过对已发表研究进行荟萃分析,确定中国产后抑郁情绪(PDM)的流行率。通过检索 PubMed、Embase、CNKI 和 CQVIP 数据库,确定了报告中国 PDM 流行率的研究。共获得 3102 篇文章,经过仔细评估,最终有 26 项研究纳入荟萃分析。这些研究共纳入 7618 例患者,其中 1621 例为 PDM。根据异质性检验和发表偏倚的可能性对这些研究进行评估。使用 Stata 软件 11.0 进行荟萃分析。随机效应模型显示,PDM 的流行率为 21%,95%置信区间(CI)为 17-25%。产后 0-1.5 个月时 PDM 发生率最高。校正发表偏倚后,PDM 水平下降至 10.4%(95%CI 9.7-11.1%,P<0.001)。敏感性分析评估了我们结果的稳定性,当排除任何一项研究时,结果均无显著变化。亚组分析显示,地区、使用的工具、抑郁评估的截断分数和时间点与 PDM 流行率呈正相关。各地区 PDM 流行率不同,中南和华东地区最低。经济发展较差地区的流行率较高,提示应更加关注西南和华北地区,并应在产后 0-1.5 个月时评估 PDM 的流行率。