非感染性前葡萄膜炎和后葡萄膜炎的视网膜中央凹浅层和深层无血管区光学相干断层扫描血管造影结果
Superficial and deep retinal foveal avascular zone OCTA findings of non-infectious anterior and posterior uveitis.
作者信息
Waizel Maria, Todorova Margarita G, Terrada Celine, LeHoang Phuc, Massamba Natalie, Bodaghi Bahram
机构信息
Department of Ophthalmology, University Hospital Basel, Mittlere Strasse 91, CH-4031, Basel, Switzerland.
University of Basel, Basel, Switzerland.
出版信息
Graefes Arch Clin Exp Ophthalmol. 2018 Oct;256(10):1977-1984. doi: 10.1007/s00417-018-4057-y. Epub 2018 Jul 6.
PURPOSE
To compare the superficial (FAZ-S) and deep foveal avascular zones (FAZ-D) of non-infectious anterior and posterior uveitis to healthy controls, using optical coherence tomography angiography (OCTA).
METHODS
OCTA was performed on 74 eyes: 34 eyes with non-infectious posterior uveitis (with (post+CME) and without macular edema (post-CME)), 11 eyes with non-infectious anterior uveitis (with (ant+CME) and without macular edema (ant-CME)), and the control group which included 29 healthy eyes.
RESULTS
Eyes suffering from non-infectious posterior uveitis presented with significantly larger FAZ-D when compared to healthy controls, both in the presence or in the absence of macular edema (p < 0.001). In the presence of macular edema, eyes presenting with anterior uveitis (ant+CME) also showed significantly larger FAZ-S (p = 0.03) and FAZ-D (p < 0.001), when compared to healthy controls. In the absence of macular edema, eyes with anterior uveitis cannot be distinguished from controls (p > 0.6).
CONCLUSION
The deep retinal foveal avascular zone seems to be enlarged in eyes presenting with non-infectious posterior uveitis, both in the presence or absence of macular edema.
目的
使用光学相干断层扫描血管造影（OCTA）比较非感染性前葡萄膜炎和后葡萄膜炎的浅表黄斑无血管区（FAZ-S）和深层黄斑无血管区（FAZ-D）与健康对照者的差异。
方法
对74只眼进行OCTA检查：34只患有非感染性后葡萄膜炎的眼（伴有（后葡萄膜炎伴黄斑囊样水肿，post+CME）和不伴有黄斑水肿（后葡萄膜炎不伴黄斑囊样水肿，post-CME）），11只患有非感染性前葡萄膜炎的眼（伴有（前葡萄膜炎伴黄斑囊样水肿，ant+CME）和不伴有黄斑水肿（前葡萄膜炎不伴黄斑囊样水肿，ant-CME）），以及包括29只健康眼的对照组。
结果
与健康对照者相比，患有非感染性后葡萄膜炎的眼，无论有无黄斑水肿，其FAZ-D均显著增大（p<0.001）。在有黄斑水肿的情况下，患有前葡萄膜炎（ant+CME）的眼与健康对照者相比，其FAZ-S也显著增大（p=0.03），FAZ-D也显著增大（p<0.001）。在无黄斑水肿的情况下，患有前葡萄膜炎的眼与对照组无明显差异（p>0.6）。
结论
无论有无黄斑水肿，患有非感染性后葡萄膜炎的眼中，视网膜深层黄斑无血管区似乎都增大。
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