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[左旋咪唑对女性慢性巨细胞病毒感染病程的影响]

[Effect of levamisole on the course of chronic cytomegalovirus infection in women].

作者信息

Martynova V N, Farber N A, Savitskiĭ G I, Demidova S A, Stepanova L G

出版信息

Vopr Virusol. 1985 Jul-Aug;30(4):440-4.

PMID:2998093
Abstract

The therapeutic effect of orally given levamisole in the treatment of women with chronic cytomegalovirus infection was studied. The patients were examined serologically, cytologically, virologically; the factors of cell-mediated immunity were also studied. Oral therapy with levamisole resulted in a definite increase of the cell-mediated immunity with a trend for decrease in antibody titres and reduced virus excretion. Evaluation of the clinical effect of levamisole therapy, however, revealed no distinct difference in the outcomes of pregnancy in the groups of women treated or not treated with levamisole.

摘要

研究了口服左旋咪唑治疗慢性巨细胞病毒感染女性的疗效。对患者进行了血清学、细胞学、病毒学检查;还研究了细胞介导免疫的相关因素。口服左旋咪唑治疗可使细胞介导免疫明显增强,抗体滴度有下降趋势,病毒排泄减少。然而,对左旋咪唑治疗临床效果的评估显示,接受或未接受左旋咪唑治疗的女性组在妊娠结局方面没有明显差异。

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