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经皮电刺激:关于其止痛效果的双盲试验

Transcutaneous electrical stimulation: a double-blind trial of its efficacy for pain.

作者信息

Thorsteinsson G, Stonnington H H, Stillwell G K, Elveback L R

出版信息

Arch Phys Med Rehabil. 1977 Jan;58(1):8-13.

PMID:299813
Abstract

A double-blind trial was done using a stimulator and a placebo device on patients who had chronic pain to determine the effectiveness of transcutaneous electrical stimulation in controlling pain. Ninety-three patients were studied, and 83 of these completed the Minnesota Multiphasic Personality Inventory (MMPI). Thirty-three patients had low-back pain and 24 had neuropathies. The stimulator was more effective than the placebo during treatment when used over the center of pain (P less than .005) or over an unrelated nerve trunk (P less than .01) and after treatment over the center of pain (P less than .05). The stimulator was significantly more effective than the placebo in neuropathies when stimulating over the related nerve trunk (P less than .005), where the stimulator response was nearly three times better than that of the placebo. The duration of subsequent relief was not significantly different after treatment with the stimulator or with the placebo device. Follow-up showed significant declines in the use and effect of the stimulator with the greatest decline noted by the depressed group.

摘要

采用刺激器和安慰剂装置对慢性疼痛患者进行了一项双盲试验,以确定经皮电刺激控制疼痛的有效性。研究了93名患者,其中83名完成了明尼苏达多相人格问卷(MMPI)。33名患者患有腰痛,24名患有神经病变。当在疼痛中心上方使用时(P<0.005)或在无关神经干上方使用时(P<0.01),以及在疼痛中心上方治疗后(P<0.05),刺激器比安慰剂在治疗期间更有效。当在相关神经干上方刺激时,刺激器在神经病变中比安慰剂显著更有效(P<0.005),刺激器的反应几乎是安慰剂的三倍。使用刺激器或安慰剂装置治疗后,后续缓解的持续时间没有显著差异。随访显示,刺激器的使用和效果显著下降,抑郁组下降最为明显。

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