Midwifery Department, Reproductive Health Promotion Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Community Nutrition, Midwifery Department, Menopause Andropause Research Center, Ahvaz Jundishapur University of Medical Sciences, 13th East Kianpars Ave, 1st Eastern Maroon, No:46, Ahvaz, Iran.
BMC Pregnancy Childbirth. 2018 Jul 7;18(1):293. doi: 10.1186/s12884-018-1832-z.
This study aimed to compare the effect of breast pump stimulation with that of oxytocin administration regarding the duration of the third stage of labor, postpartum hemorrhage, and anemia after delivery.
In this study, 108 women were randomly assigned to two groups of breast pump stimulation (n = 54) and oxytocin administration (n = 54). Women in the breast stimulation group received breast pump stimulation (10 min intermittently for each breast with a negative pressure of 250 mmHg), while the women in the oxytocin (control) group received an infusion of 30 IU oxytocin in 1000 mL of Ringer's serum with a maximum rate of 10 mL infusion per min after delivery. The duration of the third stage of labor, blood loss during the third stage of labor and 24 h after delivery, hemoglobin and hematocrit (before and 24 h after delivery), after-birth pain, and the number of breastfeedings during the 24 h after delivery were recorded. The data were analyzed using the chi-square test, independent t-test, and Wilcoxon test.
The mean duration of the third stage was 5 ± 1.97 and 5.4 ± 2.5 min in the breast stimulation and women that received intravenous oxytocin respectively (p = 0.75). Most participants had mild postpartum hemorrhage (98.1 and 96.2% in the breast stimulation and women that received intravenous oxytocin, respectively, p = 0.99). Although hemoglobin and hematocrit levels significantly decreased in both groups 24 h after delivery, there was no significant difference between both groups regarding both parameters. After-birth pain was significantly lower and the number of breastfeeding during the 24 h after delivery was significantly more in the breast stimulation group compared to the control group.
Our results demonstrated no differences between breast pump stimulation and oxytocin administration regarding the duration of the third stage of labor, postpartum hemorrhage, anaemia, after-birth pain, and the number of breastfeedings during the 24 h after delivery.
The study protocol was registered in the Iranian Randomized Controlled Trial Registry (Ref. No.: IRCT2015050722146N1 ; Registration date: 2015-11-04). The study was registered prospectively and the enrollment date was 23/8/2015.
本研究旨在比较使用吸乳器刺激和使用催产素对第三产程持续时间、产后出血和产后贫血的影响。
本研究将 108 名妇女随机分为两组，一组接受吸乳器刺激（每侧乳房 10 分钟，间歇进行，负压 250mmHg），另一组接受催产素（对照组）治疗，即分娩后在 1000ml 林格氏液中输注 30IU 催产素，最大输注速度为 10ml/分钟。记录第三产程持续时间、第三产程和产后 24 小时出血量、血红蛋白和血细胞比容（分娩前后 24 小时）、产后疼痛和产后 24 小时内哺乳次数。采用卡方检验、独立 t 检验和 Wilcoxon 检验对数据进行分析。
吸乳器刺激组第三产程平均持续时间为 5±1.97 分钟，静脉注射催产素组为 5.4±2.5 分钟（p=0.75）。大多数参与者出现轻度产后出血（吸乳器刺激组和静脉注射催产素组分别为 98.1%和 96.2%，p=0.99）。两组产后 24 小时血红蛋白和血细胞比容水平均显著下降，但两组间无显著差异。与对照组相比，吸乳器刺激组产后疼痛明显减轻，产后 24 小时内哺乳次数明显增多。
与催产素给药相比，吸乳器刺激对第三产程持续时间、产后出血、贫血、产后疼痛和产后 24 小时内哺乳次数无影响。
该研究方案在伊朗随机对照试验注册中心注册（注册号：IRCT2015050722146N1；注册日期：2015 年 11 月 4 日）。该研究是前瞻性注册的，登记日期为 2015 年 8 月 23 日。
