Dumas Ryan P, Subramanian Madhu, Hodgman Erica, Arevalo Michelle, Nguyen Gabriella, Li Kevin, Aijwe Tochi, Williams Brian, Eastman Alexander, Luk Stephen, Minshall Christian, Cripps Michael W
Am Surg. 2018 Jun 1;84(6):1110-1116.
Laparoscopic appendectomy (LA) is the standard of care for the treatment of acute appendicitis. There is an ongoing debate regarding the optimal management of appendicitis, which led us to study outcomes after an appendectomy at a large safety-net hospital. We hypothesize that despite a high-risk population, LA remains a safe and effective treatment for acute appendicitis. A retrospective review was performed of all patients who underwent an appendectomy from 2011 to 2013. The primary end point was significant morbidity defined as a score of three or greater on the Clavien-Dindo scale of surgical morbidity. Thousand hundred and sixty-four patients underwent an appendectomy. A total of 1102 (94.7%) patients underwent either an LA or laparoscopic converted to open appendectomy, and 62 (5.3%) patients underwent an open appendectomy (OA). Two hundred and forty six patients (21.1%) had complicated appendicitis. Laparoscopic converted to OA conversion rate was 4.4 per cent and differed between years (P < 0.001). LA had a significantly shorter length of stay, shorter length of postoperative antibiotics, and less postoperative morbidity. When limited to only patients with complicated appendicitis, major morbidity was still greater in the OA group (22.6 vs 52.0%, P = 0.001). Length of stay was significantly longer in the OA group [3.42 (2.01, 5.97) vs 7.04 (5.05, 10.13), P < 0.001]. Odds for complication were 2.6 times greater in the OA group compared with the LA group. In the absence of peritonitis and systemic illness necessitating urgent laparotomy, patients who are laparoscopic surgical candidates should be offered an LA. Our study demonstrates that these patients have better outcomes and shorter hospital stays.
腹腔镜阑尾切除术(LA)是治疗急性阑尾炎的标准治疗方法。关于阑尾炎的最佳治疗管理存在持续的争论,这促使我们在一家大型安全网医院研究阑尾切除术后的结果。我们假设,尽管患者群体风险较高,但LA仍然是治疗急性阑尾炎的一种安全有效的方法。对2011年至2013年期间接受阑尾切除术的所有患者进行了回顾性研究。主要终点是严重并发症,定义为根据Clavien-Dindo手术并发症分级量表评分为3分或更高。164例患者接受了阑尾切除术。共有1102例(94.7%)患者接受了LA或腹腔镜中转开腹阑尾切除术,62例(5.3%)患者接受了开腹阑尾切除术(OA)。246例患者(21.1%)患有复杂性阑尾炎。腹腔镜中转开腹的转换率为4.4%,且各年份之间存在差异(P<0.001)。LA的住院时间显著更短,术后抗生素使用时间更短,术后并发症更少。当仅局限于患有复杂性阑尾炎的患者时,OA组的主要并发症仍然更高(22.6%对52.0%,P = 0.001)。OA组的住院时间显著更长[3.42(2.01,5.97)对7.04(5.05,10.13),P<0.001]。OA组发生并发症的几率是LA组的2.6倍。在没有腹膜炎和需要紧急剖腹手术的全身性疾病的情况下,对于适合腹腔镜手术的患者应提供LA。我们的研究表明,这些患者有更好的结果和更短的住院时间。