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精液中的血管紧张素转换酶及其在获能过程中的可能作用。

Angiotensin converting enzyme in semen and its possible role in capacitation.

作者信息

Singh U S, Kumar M V, Panda J N

出版信息

Andrologia. 1985 Sep-Oct;17(5):472-5. doi: 10.1111/j.1439-0272.1985.tb01044.x.

DOI:10.1111/j.1439-0272.1985.tb01044.x
PMID:2998227
Abstract

Angiotensin Converting Enzyme (ACE) is present in the testis, epididymis and semen. But no physiological role has been assigned to ACE. The present study is to indicate possible role of ACE in capacitation. Semen was incubated in minimum capacitation in vitro. Epinephrine and serotonin were added to note the effect of biogenic amines. The leakage of ACE was very high in capacitated spermatozoa compared to spermatozoa in saline. Presence of amines in the saline induced ACE leakage. These results indicate that ACE may be involved in the capacitation.

摘要

血管紧张素转换酶(ACE)存在于睾丸、附睾和精液中。但尚未确定ACE的生理作用。本研究旨在表明ACE在精子获能中的可能作用。精液在体外进行最低限度的获能培养。添加肾上腺素和血清素以观察生物胺的作用。与盐溶液中的精子相比,获能精子中ACE的泄漏率非常高。盐溶液中胺的存在会诱导ACE泄漏。这些结果表明ACE可能参与了精子获能过程。

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