• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肝切除类型和切除量对结直肠癌转移患者生存的影响。

Influence of the Type and Amount of Liver Resection on the Survival of the Patients with Colorectal Metastases.

作者信息

Petrovski Stefan, Karakolevska-Ilova Marija, Simeonovska-Joveva Elena, Serafimov Aleksandar, Adzi-Andov Ljubica, Dimitrova Violeta

机构信息

Clinical Hospital Shtip, Surgery, Ljuben Ivanov bb, Shtip, Republic of Macedonia.

Clinical Hospital Shtip, Oncology, Shtip, Republic of Macedonia.

出版信息

Open Access Maced J Med Sci. 2018 Jun 9;6(6):1046-1051. doi: 10.3889/oamjms.2018.116. eCollection 2018 Jun 20.

DOI:10.3889/oamjms.2018.116
PMID:29983799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6026431/
Abstract

INTRODUCTION

Colorectal liver metastases have a poor prognosis, and only 2% have an average 5-year survival if left untreated. Despite radical resection, the average five-year survival is between 25% and 44%.

AIM

To explore the experience of the Clinic in the treatment of colorectal liver metastases, comparing it with data from the literature and based on the comparison to determine the influence of the type and extensity of resection survival after radical surgical treatment of patients.

METHODS

This is a retrospective study. The study comprised the period between 01.01.2006 to 31.12.2015. It included a total of 239 cases, of whom: 179 patients underwent radical interventions, 5 palliative and 55 patients underwent explorative interventions due to liver metastases.

RESULTS

Radical resection of liver metastases has the impact of the patient survival, and the survival is the smallest in the patients with left hemihepatectomy and the longest in the patients with bisegmentectomy. But no specific technique and the number of resected segments influenced the survival of patients with colorectal liver metastases.

CONCLUSION

In patients with colorectal liver metastases only resection has potentially curative character. The type and amount of liver resection has no influence of the survival.

摘要

引言

结直肠癌肝转移预后较差,若不治疗,仅有2%的患者平均5年生存率。尽管进行了根治性切除,平均5年生存率仍在25%至44%之间。

目的

探讨本诊所治疗结直肠癌肝转移的经验,与文献数据进行比较,并基于比较结果确定根治性手术治疗后切除类型和范围对患者生存的影响。

方法

这是一项回顾性研究。研究涵盖2006年1月1日至2015年12月31日期间。共纳入239例病例,其中:179例患者接受了根治性干预,5例接受姑息性治疗,55例因肝转移接受探查性干预。

结果

肝转移瘤的根治性切除对患者生存有影响,左半肝切除患者的生存率最低,双段切除患者的生存率最长。但没有特定技术和切除段数影响结直肠癌肝转移患者的生存。

结论

对于结直肠癌肝转移患者,只有切除具有潜在治愈性。肝切除的类型和范围对生存无影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/7b9a295ee341/OAMJMS-6-1046-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/b8a88113001d/OAMJMS-6-1046-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/bb7863beb520/OAMJMS-6-1046-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/95eddf9c9c79/OAMJMS-6-1046-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/7b9a295ee341/OAMJMS-6-1046-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/b8a88113001d/OAMJMS-6-1046-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/bb7863beb520/OAMJMS-6-1046-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/95eddf9c9c79/OAMJMS-6-1046-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f04/6026431/7b9a295ee341/OAMJMS-6-1046-g004.jpg

相似文献

1
Influence of the Type and Amount of Liver Resection on the Survival of the Patients with Colorectal Metastases.肝切除类型和切除量对结直肠癌转移患者生存的影响。
Open Access Maced J Med Sci. 2018 Jun 9;6(6):1046-1051. doi: 10.3889/oamjms.2018.116. eCollection 2018 Jun 20.
2
[Radiofrequency ablation of colorectal liver metastases].[结直肠癌肝转移的射频消融术]
Zentralbl Chir. 2009 Apr;134(2):145-8. doi: 10.1055/s-2008-1076874. Epub 2009 Apr 20.
3
Is carcino-embryonic antigen useful in the follow-up management of patients with colorectal liver metastases?癌胚抗原在结直肠癌肝转移患者的随访管理中有用吗?
Am J Surg. 1999 Jan;177(1):2-6. doi: 10.1016/s0002-9610(98)00303-1.
4
Comparison of Total Tumor Volume, Size and Number of Colorectal Liver Metastases in Prediction of Survival in Patients after Liver Resection.肝切除术后患者生存预测中结直肠癌肝转移瘤总体积、大小及数量的比较
Pol Przegl Chir. 2015 Feb;87(2):53-8. doi: 10.1515/pjs-2015-0019.
5
Influence of postoperative morbidity on long-term survival following liver resection for colorectal metastases.结直肠癌肝转移切除术后并发症对长期生存的影响。
Br J Surg. 2003 Sep;90(9):1131-6. doi: 10.1002/bjs.4202.
6
Curative-intent treatment of recurrent colorectal liver metastases: A comparison between ablation and resection.复发性结直肠癌肝转移的根治性治疗:消融与切除的比较
Eur J Surg Oncol. 2017 Oct;43(10):1901-1907. doi: 10.1016/j.ejso.2017.08.008. Epub 2017 Aug 26.
7
Classifying the stage IV colorectal cancer: prognostic impact of radical resection for colorectal liver metastases and proposal for a new staging system.四期结直肠癌的分类:结直肠肝转移根治性切除的预后影响及新分期系统的建议。
Cell Biochem Biophys. 2013;67(3):1445-9. doi: 10.1007/s12013-013-9577-9.
8
[Surgical resection of colorectal liver metastases: Gold standard for solitary and radically resectable lesions].[结直肠癌肝转移的手术切除:孤立性及可根治性切除病灶的金标准]
Swiss Surg. 1996;Suppl 4:4-17.
9
Adjuvant systemic chemotherapy after putative curative resection of colorectal liver and lung metastases.结直肠肝肺转移瘤潜在治愈性切除术后辅助全身化疗。
Clin Colorectal Cancer. 2013 Sep;12(3):188-94. doi: 10.1016/j.clcc.2013.04.002. Epub 2013 Jun 14.
10
[Repeat liver resection in colorectal liver metastases].[结直肠癌肝转移的再次肝切除术]
Langenbecks Arch Chir. 1995;380(4):229-34.

本文引用的文献

1
Outcomes of laparoscopic and open resection for neuroendocrine liver metastases.腹腔镜与开腹手术切除治疗神经内分泌肝脏转移瘤的效果比较。
Surgery. 2012 Dec;152(6):1225-31. doi: 10.1016/j.surg.2012.08.027. Epub 2012 Oct 13.
2
Anatomical versus nonanatomical resection of colorectal liver metastases: is there a difference in surgical and oncological outcome?结直肠肝转移的解剖性与非解剖性切除术:手术和肿瘤学结果有差异吗?
World J Surg. 2011 Mar;35(3):656-61. doi: 10.1007/s00268-010-0890-9.
3
Comparison of simultaneous or delayed liver surgery for limited synchronous colorectal metastases.
同期或延期肝切除术治疗局限型同步结直肠转移瘤的比较。
Br J Surg. 2010 Aug;97(8):1279-89. doi: 10.1002/bjs.7106.
4
Body mass index and adverse perioperative outcomes following hepatic resection.体重指数与肝切除术后不良围手术期结局。
J Gastrointest Surg. 2010 Aug;14(8):1285-91. doi: 10.1007/s11605-010-1232-9. Epub 2010 Jun 8.
5
Trends in perioperative outcome after hepatic resection: analysis of 1500 consecutive unselected cases over 20 years.肝切除术后围手术期结局的趋势:对20年间1500例连续入选的非选择性病例的分析。
Ann Surg. 2009 Jun;249(6):995-1002. doi: 10.1097/SLA.0b013e3181a63c74.
6
Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases.初始不可切除的转移性结直肠癌患者接受氟尿嘧啶/亚叶酸钙、奥沙利铂和伊立替康(FOLFOXIRI)治疗后行转移灶根治性手术的长期预后。
Ann Surg. 2009 Mar;249(3):420-5. doi: 10.1097/SLA.0b013e31819a0486.
7
Treatment of colorectal liver metastases: a review.结直肠癌肝转移的治疗:综述
Rev Recent Clin Trials. 2009 Jan;4(1):56-62. doi: 10.2174/157488709787047558.
8
Does anatomic versus nonanatomic resection affect recurrence and survival in patients undergoing surgery for colorectal liver metastasis?对于接受结直肠癌肝转移手术的患者,解剖性切除与非解剖性切除会影响复发率和生存率吗?
Ann Surg Oncol. 2009 Feb;16(2):379-84. doi: 10.1245/s10434-008-0218-2. Epub 2008 Nov 20.
9
Urgent need for a new staging system in advanced colorectal cancer.晚期结直肠癌迫切需要一种新的分期系统。
J Clin Oncol. 2008 Oct 10;26(29):4828-33. doi: 10.1200/JCO.2008.17.6453. Epub 2008 Aug 18.
10
Impact of type of liver resection on the outcome of colorectal liver metastases: a case-matched analysis.肝切除类型对结直肠癌肝转移预后的影响:一项病例匹配分析。
J Surg Oncol. 2008 May 1;97(6):503-7. doi: 10.1002/jso.20979.