[9-脱氮肌苷的无环类似物及相关化合物的合成与性质]
[Synthesis and properties of an acyclic analog of 9-deazainosine and related compounds].
作者信息
Ektova L V, Tolkachev V N, Sizova O S, Nikolaeva T G, Pilipenko T V
出版信息
Bioorg Khim. 1985 Aug;11(8):1105-9.
PMID:2998402
Abstract
An acyclic analogue of 9-deazainosine, 9-(2-hydroxyethoxymethyl)-9-deazahypoxanthine, and related compounds have been synthesized starting from 9-(hydroxyethyl)-9-deazahypoxanthine. The acyclo-9-deazainosine exhibited some cytotoxic activity.
摘要
9-(2-羟乙氧基甲基)-9-脱氮次黄嘌呤，一种9-脱氮肌苷的无环类似物，以及相关化合物已从9-(羟乙基)-9-脱氮次黄嘌呤开始合成。无环9-脱氮肌苷表现出一些细胞毒性活性。
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