Methotrexate inhibits the leukotriene B4 induced intraepidermal accumulation of polymorphonuclear leukocytes.
作者信息
van de Kerkhof P C, Bauer F W, Maassen-de Grood R M
出版信息
Br J Dermatol. 1985 Sep;113(3):251a-255a. doi: 10.1111/j.1365-2133.1985.tb02075.x.
Abstract
The penetration of polymorphonuclear leukocytes (PMNs) into the epidermis following topical application of leukotriene B4 was assessed in the clinically uninvolved skin of psoriatic patients treated with methotrexate and of psoriatic patients without treatment, and in normal controls. Inhibition of PMN infiltration was observed in those patients treated with methotrexate while there was no significant difference between untreated psoriatic patients and normal controls.
摘要
相似文献
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Methotrexate inhibits the leukotriene B4 induced intraepidermal accumulation of polymorphonuclear leukocytes.
Br J Dermatol. 1985 Sep;113(3):251a-255a. doi: 10.1111/j.1365-2133.1985.tb02075.x.
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