Department of Ophthalmology, SUNY Downstate Medical Center, Brooklyn, NY.
Curr Opin Ophthalmol. 2018 Sep;29(5):445-450. doi: 10.1097/ICU.0000000000000505.
Periocular sebaceous cell carcinoma is a rare malignancy that is often misdiagnosed leading to increased morbidity and mortality. This review aims to describe current knowledge on the disease to aid clinicians in timely diagnosis and treatment.
New research has shown that the diagnosis of sebaceous cell carcinoma can be aided with immunohistochemical stains. A revision in the American Joint Committee on Cancer staging system incorporates new tumor size classifications in the staging of eyelid carcinomas. Wide local excision and Mohs micrographic surgery continue to represent the standard of care for initial treatment of localized disease.
The current review highlights diagnostic and treatment modalities to allow clinicians to make timely diagnosis and tailor treatment plans for individual patient presentations.
眼周皮脂细胞癌是一种罕见的恶性肿瘤，常被误诊，导致发病率和死亡率增加。本综述旨在描述该疾病的现有知识，以帮助临床医生及时诊断和治疗。
新的研究表明，免疫组织化学染色可辅助皮脂细胞癌的诊断。美国癌症联合委员会分期系统的修订纳入了新的肿瘤大小分类，用于眼睑癌的分期。广泛局部切除和 Mohs 显微外科手术仍然是局部疾病初始治疗的标准。
本综述强调了诊断和治疗方法，使临床医生能够及时诊断，并根据患者的具体情况制定治疗计划。
