Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing, China.
Clin Infect Dis. 2019 Jan 18;68(3):505-510. doi: 10.1093/cid/ciy566.
Gonococcal antimicrobial resistance (AMR) has become a global threat significantly hampering the control of gonorrhea. Many socioeconomic, biological, behavioral, and programmatic factors have played an important role in driving the emergence, transmission and spread of gonococcal AMR. However, research to address these scientific and programmatic questions is limited in China. Here we propose a ROADMAP (acronym for resistance surveillance, outcomes due to AMR, antibiotic stewardship and application, diagnostic tools, mechanisms of AMR, antimicrobial assessment, and population pharmacokinetics and pharmacodynamics) plan for expanding interdisciplinary collaborations to address the research needs in China.
淋球菌抗菌药物耐药性（AMR）已成为全球威胁，严重阻碍了淋病的控制。许多社会经济、生物学、行为学和规划因素在推动淋球菌 AMR 的出现、传播和扩散方面发挥了重要作用。然而，针对这些科学和规划问题的研究在中国受到限制。在这里，我们提出了一个 ROADMAP（耐药监测、AMR 导致的结果、抗生素管理和应用、诊断工具、AMR 机制、抗菌药物评估以及人群药代动力学和药效动力学）计划，以扩大跨学科合作，满足中国的研究需求。
