Ryder K W, Epinette W W, Jay S J, Ransburg R C, Glick M R
Clin Chim Acta. 1985 Dec 13;153(2):143-6. doi: 10.1016/0009-8981(85)90165-2.
Serum angiotensin converting enzyme activity is frequently increased in patients with active sarcoidosis. In spite of a reported association between sarcoidosis and psoriasis, serum angiotensin converting enzyme activities have not been reported for patients with psoriasis. We found the mean (SD) angiotensin-converting enzyme activity for 51 healthy subjects was 18.6 (5.8) kU/l, but for 52 patients with psoriasis without coexisting sarcoidosis, it was 28.3 (6.7) kU/l. There is a significant difference between these means (p less than 0.01). Forty-two percent (22/52) of the psoriasis patients had an increased serum angiotensin converting activity. Other diseases sometimes associated with an increased serum angiotensin converting enzyme activity were excluded as possible causes of a elevated activity in our patients with psoriasis. We conclude that almost half of the patients with psoriasis will have an elevated serum angiotensin converting enzyme activity, even when coexisting sarcoidosis is absent.
在结节病活动期患者中，血清血管紧张素转换酶活性常常升高。尽管有报道称结节病与银屑病之间存在关联，但尚未有关于银屑病患者血清血管紧张素转换酶活性的报道。我们发现，51名健康受试者的血管紧张素转换酶活性均值（标准差）为18.6（5.8）kU/l，而52名无结节病并存的银屑病患者的该活性均值为28.3（6.7）kU/l。这些均值之间存在显著差异（p小于0.01）。42%（22/52）的银屑病患者血清血管紧张素转换活性升高。其他有时与血清血管紧张素转换酶活性升高相关的疾病被排除，不作为我们银屑病患者活性升高的可能原因。我们得出结论，即使不存在并存的结节病，近一半的银屑病患者血清血管紧张素转换酶活性也会升高。
