Voiculescu V M, Lupu M, Papagheorghe L, Giurcaneanu C, Micu E
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; "Elias" University Emergency Hospital, Bucharest, Romania.
"Elias" University Emergency Hospital, Bucharest, Romania.
J Med Life. 2014 Oct-Dec;7(4):468-71.
Psoriasis is a chronic inflammatory disease, predominantly affecting the skin, being included in the group of Immune Mediated Inflammatory Diseases. Growing evidence from the last 10 years suggests that several systemic conditions like metabolic syndrome, cardiovascular disease, diabetes, psychological disorders or inflammatory bowel disease are prevalent in psoriasis patients. The linker might be the chronic secretion of pro-inflammatory cytokines. In this current review, the scientific evidence that explains the relationship between psoriasis and the metabolic syndrome in particular will be addressed, as the metabolic syndrome comprises a group of risk factors for cardiovascular disease, thus offering an overall picture of the systemic involvement in psoriasis. An integrated approach, with an early detection and treatment of the components of the metabolic syndrome, are important steps in psoriasis management. Attention should be paid on influence of psoriasis treatment upon comorbidities and vice-versa.
银屑病是一种慢性炎症性疾病，主要累及皮肤，属于免疫介导的炎症性疾病范畴。过去10年越来越多的证据表明，银屑病患者中普遍存在几种全身性疾病，如代谢综合征、心血管疾病、糖尿病、心理障碍或炎症性肠病。其中的联系可能在于促炎细胞因子的慢性分泌。在本综述中，将阐述解释银屑病与代谢综合征之间关系的科学证据，因为代谢综合征包含一组心血管疾病的危险因素，从而全面呈现银屑病的全身性病变情况。采用综合方法，早期发现并治疗代谢综合征的各个组成部分，是银屑病管理的重要步骤。应关注银屑病治疗对合并症的影响，反之亦然。
