痛风：不可改变和可改变的危险因素综述
Gout: a review of nonmodifiable and modifiable risk factors.
作者信息
MacFarlane Lindsey A, Kim Seoyoung C
机构信息
Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA; Division of Rheumatology, Allergy and Immunology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
出版信息
Rheum Dis Clin North Am. 2014 Nov;40(4):581-604. doi: 10.1016/j.rdc.2014.07.002. Epub 2014 Sep 2.
Gout is a common inflammatory arthritis triggered by the crystallization of uric acid within the joints. Gout affects millions worldwide and has an increasing prevalence. Recent research has been carried out to better qualify and quantify the risk factors predisposing individuals to gout. These can largely be broken into nonmodifiable risk factors, such as gender, age, race, and genetics, and modifiable risk factors, such as diet and lifestyle. Increasing knowledge of factors predisposing certain individuals to gout could potentially lead to improved preventive practices. This review summarizes the nonmodifiable and modifiable risk factors associated with development of gout.
痛风是一种常见的炎性关节炎，由关节内尿酸结晶引发。痛风影响着全球数百万人，且患病率不断上升。最近已开展研究，以更好地界定和量化使个体易患痛风的风险因素。这些因素大致可分为不可改变的风险因素，如性别、年龄、种族和遗传因素，以及可改变的风险因素，如饮食和生活方式。对使某些个体易患痛风的因素了解得越来越多，可能会带来更好的预防措施。本综述总结了与痛风发病相关的不可改变和可改变的风险因素。
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