Lass-Flörl Cornelia
Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Schöpfstraße 41, 6020 Innsbruck, Austria.
J Fungi (Basel). 2018 Jul 9;4(3):83. doi: 10.3390/jof4030083.
The species complex is found in a wide variety of habitats, and the spectrum of diseases caused covers allergic bronchopulmonary aspergillosis, bronchitis and/or tracheobronchitis, and invasive and disseminated aspergillosis. Invasive infections are a significant cause of morbidity and mortality mainly in patients with hematological malignancy. The section covers a total of 16 accepted species of which most are amphotericin B resistant. Triazoles are the preferred agents for treatment and prevention of invasive aspergillosis. Poor prognosis in patients with invasive infections seems to be independent of anti- azole-based treatment.
该菌种复合体存在于多种生境中，其所引发的疾病谱涵盖过敏性支气管肺曲霉病、支气管炎和/或气管支气管炎，以及侵袭性和播散性曲霉病。侵袭性感染主要是血液系统恶性肿瘤患者发病和死亡的重要原因。该部分总共涵盖16个公认的菌种，其中大多数对两性霉素B耐药。三唑类药物是治疗和预防侵袭性曲霉病的首选药物。侵袭性感染患者预后不良似乎与基于抗唑类的治疗无关。
