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Alterations in Polyunsaturated Fatty Acid Metabolism and Reduced Serum Eicosadienoic Acid Level in Ulcerative Colitis: Is There a Place for Metabolomic Fatty Acid Biomarkers in IBD?

作者信息

Sitkin Stanislav, Pokrotnieks Juris

机构信息

Department of Internal Diseases, Gastroenterology and Dietetics, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.

Department of Internal Diseases, Rīga Stradiņš University, Riga, Latvia.

出版信息

Dig Dis Sci. 2018 Sep;63(9):2480-2481. doi: 10.1007/s10620-018-5182-5. Epub 2018 Jul 9.

DOI:10.1007/s10620-018-5182-5
PMID:29987625
Abstract
摘要

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本文引用的文献

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Alterations in Docosahexaenoic Acid-Related Lipid Cascades in Inflammatory Bowel Disease Model Mice.二十二碳六烯酸相关脂质级联反应在炎症性肠病模型小鼠中的改变。
Dig Dis Sci. 2018 Jun;63(6):1485-1496. doi: 10.1007/s10620-018-5025-4. Epub 2018 Mar 21.
2
Protectin D1 and resolvin D5 are effectors of intestinal protection.保护素 D1 和分辨率素 D5 是肠道保护的效应物。
Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3963-3968. doi: 10.1073/pnas.1617290114. Epub 2017 Mar 29.
3
Serum Fatty Acids Are Correlated with Inflammatory Cytokines in Ulcerative Colitis.
Erythrocyte n-6 Fatty Acids and Risk for Cardiovascular Outcomes and Total Mortality in the Framingham Heart Study.
红细胞 n-6 脂肪酸与弗雷明汉心脏研究中心血管结局和全因死亡率的关系。
Nutrients. 2018 Dec 19;10(12):2012. doi: 10.3390/nu10122012.
血清脂肪酸与溃疡性结肠炎中的炎性细胞因子相关。
PLoS One. 2016 May 26;11(5):e0156387. doi: 10.1371/journal.pone.0156387. eCollection 2016.
4
Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes.γ-亚麻酸、二高-γ-亚麻酸、类二十烷酸与炎症过程
Eur J Pharmacol. 2016 Aug 15;785:77-86. doi: 10.1016/j.ejphar.2016.04.020. Epub 2016 Apr 12.
5
DHA protects against experimental colitis in IL-10-deficient mice associated with the modulation of intestinal epithelial barrier function.二十二碳六烯酸（DHA）可保护白细胞介素-10缺乏的小鼠免受实验性结肠炎的侵害，这与肠道上皮屏障功能的调节有关。
Br J Nutr. 2015 Jul;114(2):181-8. doi: 10.1017/S0007114515001294.
6
Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways.缺氧通过HIF1α依赖性和非依赖性途径诱导脂肪生成的癌细胞表型。
Oncotarget. 2015 Feb 10;6(4):1920-41. doi: 10.18632/oncotarget.3058.
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Nutritional modulators of ulcerative colitis: clinical efficacies and mechanistic view.溃疡性结肠炎的营养调节剂：临床疗效和机制观点。
World J Gastroenterol. 2013 Feb 21;19(7):994-1004. doi: 10.3748/wjg.v19.i7.994.
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Association of n-3 and n-6 long-chain polyunsaturated fatty acids in plasma lipid classes with inflammatory bowel diseases.血浆脂质类别中n-3和n-6长链多不饱和脂肪酸与炎症性肠病的关联。
Br J Nutr. 2007 Jun;97(6):1154-61. doi: 10.1017/S0007114507682956. Epub 2007 Mar 8.