Mueller-Schuessele Stefanie J, Michaud Morgane
INRES-Chemical Signalling, University of Bonn, Bonn, Germany.
Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA.
Methods Mol Biol. 2018;1829:87-109. doi: 10.1007/978-1-4939-8654-5_6.
Plastids are organelles delineated by two envelopes that play important roles in different cellular processes such as energy production or lipid biosynthesis. To regulate their biogenesis and their function, plastids have to communicate with other cellular compartments. This communication can be mediated by signaling molecules and by the establishment of direct contacts between the plastid envelope and other organelles such as the endoplasmic reticulum, the mitochondria, the plasma membrane, the peroxisomes and the nucleus. These interactions are highly dynamic and respond to different biotic and abiotic stresses. However, the mechanisms involved in the formation of plastid-organelle contact sites and their functions are still enigmatic. In this chapter, we summarize our current knowledge about plastid contact sites and their role in the regulation of plastid biogenesis and function.
质体是由两层包膜界定的细胞器，在能量产生或脂质生物合成等不同细胞过程中发挥重要作用。为了调节其生物发生和功能，质体必须与其他细胞区室进行通讯。这种通讯可以由信号分子介导，也可以通过质体包膜与其他细胞器（如内质网、线粒体、质膜、过氧化物酶体和细胞核）之间建立直接接触来实现。这些相互作用是高度动态的，并对不同的生物和非生物胁迫作出反应。然而，参与质体-细胞器接触位点形成的机制及其功能仍然是个谜。在本章中，我们总结了目前关于质体接触位点及其在质体生物发生和功能调节中的作用的知识。
