Lourdudoss Cecilia, Arnaud Laurent, Wolk Alicja, van Vollenhoven Ronald F, Di Giuseppe Daniela
ClinTRID, D1:00, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden.
Institute of Environmental Medicine (IMM), C6, Nutritional Epidemiology, Box 210, 17177 Stockholm, Sweden.
Int J Rheumatol. 2018 Jun 11;2018:9152480. doi: 10.1155/2018/9152480. eCollection 2018.
To investigate long-term dietary changes after rheumatoid arthritis (RA) diagnosis in Swedish women, compared to women without RA.
This study included 21,602 women from the Swedish Mammography Cohort (SMC), who completed dietary questionnaires in 1997 and 2009. Between 1997 and 2009, 191 women were diagnosed with RA. Dietary changes after RA diagnosis were analyzed based on intake of 82 food items. Statistical analysis included linear mixed models.
Women with RA, compared to women without RA, had significantly lower intake (mean servings per week) of animal products such as black pudding, egg, kidney, and liver paste (2.94±2.73 versus 2.45±1.82, p=0.010) and dairy products (35.14±20.02 versus 28.42±16.10, p=0.040) in 1997 and of cereals and grains (31.01±15.54 versus 28.00±14.98, p=0.009) in 2009. However, multivariable adjusted changes in dietary intake from 1997 to 2009 did not show any significant difference in intake. Nevertheless, women without RA increased their intake of whole wheat bread, wheat/oat bran, and rice more than women with RA.
Women who had been diagnosed with RA had similar dietary patterns over time as the general population; these women did not remarkably change their diet over time due to their disease. Dietary recommendations for RA patients are needed.
与未患类风湿性关节炎（RA）的女性相比，调查瑞典女性在确诊RA后的长期饮食变化。
本研究纳入了瑞典乳腺X线摄影队列（SMC）中的21602名女性，她们在1997年和2009年完成了饮食调查问卷。1997年至2009年间，191名女性被诊断为RA。基于82种食物的摄入量分析RA诊断后的饮食变化。统计分析包括线性混合模型。
与未患RA的女性相比，患RA的女性在1997年动物制品如黑布丁、鸡蛋、肾脏和肝酱的摄入量（每周平均份数）显著更低（2.94±2.73对2.45±1.82，p=0.010），乳制品摄入量也显著更低（35.14±20.02对28.42±16.10，p=0.040）；在2009年谷物和谷类的摄入量显著更低（31.01±15.54对28.00±14.98，p=0.009）。然而，1997年至2009年饮食摄入量的多变量调整变化未显示出摄入量有任何显著差异。尽管如此，未患RA的女性全麦面包、小麦/燕麦麸和大米的摄入量比患RA的女性增加得更多。
被诊断为RA的女性随着时间推移的饮食模式与普通人群相似；这些女性并未因其疾病而随着时间显著改变饮食。需要针对RA患者的饮食建议。
