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食用肉类和奶制品与女性患类风湿关节炎的风险无关:一项基于人群的队列研究。

Consumption of Meat and Dairy Products Is Not Associated with the Risk for Rheumatoid Arthritis among Women: A Population-Based Cohort Study.

机构信息

Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, 90187 Umeå, Sweden.

Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, 171 77 Solna, Sweden.

出版信息

Nutrients. 2019 Nov 19;11(11):2825. doi: 10.3390/nu11112825.

Abstract

Diet has gained attention as a risk factor for the development of rheumatoid arthritis (RA), especially with regards to food of animal origin, such as meat and dairy products. By using data from national patient registers and dietary data from a large prospective population cohort, the Swedish Mammography Cohort, we aimed to investigate whether the consumption of meat and dairy products had any impact on the risk of subsequent development of RA. During 12 years of follow-up (January 2003-December 2014; 381, 456 person-years), 368 patients with a new diagnosis of RA were identified. No associations between the development of RA and the consumption of meat and meat products (hazard ratio [HR] for the fully adjusted model: 1.08 [95% CI: 0.77-1.53]) or the total consumption of milk and dairy products (HR for the fully adjusted model: 1.09 [95% CI: 0.76-1.55]) were observed. In conclusion, in this large prospective cohort of women, no associations were observed between dietary intake of meat and dairy products and the risk of RA development.

摘要

饮食被认为是类风湿关节炎(RA)发展的一个风险因素,特别是与动物源性食物,如肉类和奶制品有关。通过使用来自国家患者登记处的数据和来自大型前瞻性人群队列——瑞典乳腺摄影队列的饮食数据,我们旨在研究肉类和奶制品的消费是否会对随后发生 RA 的风险产生影响。在 12 年的随访期间(2003 年 1 月至 2014 年 12 月;381,456 人年),确定了 368 例新诊断为 RA 的患者。RA 发展与肉类和肉类产品的消费(完全调整模型的风险比 [HR]:1.08 [95%置信区间:0.77-1.53])或牛奶和奶制品总摄入量(完全调整模型的 HR:1.09 [95%CI:0.76-1.55])之间没有关联。总之,在这项大型前瞻性女性队列研究中,饮食中肉类和奶制品的摄入与 RA 发展风险之间没有观察到关联。

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