Lotz J P, Colbert N, Degott C, Pariente E A
J Clin Gastroenterol. 1985 Oct;7(5):438-40. doi: 10.1097/00004836-198510000-00015.
A patient with long-standing Waldenström's disease and cryoglobulinemia, treated with chlorambucil, developed hepatocellular carcinoma. Although HBs antigen, anti-HBs, and anti-HBc antibodies were not detected in his serum by conventional polyclonal radioimmunoassays, immunofluorescence techniques showed HBs antigen to be present in hepatocytes.
一名患有长期瓦尔登斯特伦病和冷球蛋白血症的患者，接受苯丁酸氮芥治疗后发生了肝细胞癌。尽管通过传统的多克隆放射免疫测定法在其血清中未检测到乙肝表面抗原、乙肝表面抗体和乙肝核心抗体，但免疫荧光技术显示肝细胞中存在乙肝表面抗原。
