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Vaccine. 2015 Aug 26;33(36):4398-405. doi: 10.1016/j.vaccine.2015.07.035. Epub 2015 Jul 22.
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2008年至2016年向疫苗不良事件报告系统（VAERS）报告的服用第一剂轮状病毒疫苗（罗特威和Rotarix）后出现下呼吸道感染的情况。

Reports of lower respiratory tract infection following dose 1 of RotaTeq and Rotarix vaccines to the Vaccine Adverse Event Reporting System (VAERS), 2008-2016.

作者信息

Haber Penina, Amin Muhammad, Ng Carmen, Weintraub Eric, McNeil Michael M

机构信息

a Immunization Safety Office, Centers for Disease Control and Prevention , Atlanta , GA , USA.

出版信息

Hum Vaccin Immunother. 2018;14(11):2755-2759. doi: 10.1080/21645515.2018.1491509. Epub 2018 Jul 26.

DOI:10.1080/21645515.2018.1491509
PMID:29993327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6314423/
Abstract

A 2018 manufacturer post-licensure safety study identified a possible association between Rotarix (RV1) rotavirus vaccine and lower respiratory tract infections (LRTI) in infants within 0-6 days following receipt of RV1 dose 1. We reviewed reports to the Vaccine Adverse Event Reporting System (VAERS) of LRTI occurring 0-6 days and 0-29 days post vaccination following RotaTeq (RV5) or Rotarix (RV1) vaccinations in conjunction with either Prevnar (PCV7) or Prevnar 13 (PCV13), in infants aged 6 to 15 weeks. There was no significant difference in LRTI reports to VAERS in the 0-6 days and 0-29 days following receipt of either RV5 or RV1 given with either pneumococcal vaccine.

摘要

一项2018年的制造商上市后安全性研究发现，Rotarix（RV1）轮状病毒疫苗与接种RV1第1剂后0至6天内婴儿的下呼吸道感染（LRTI）之间可能存在关联。我们回顾了向疫苗不良事件报告系统（VAERS）提交的报告，这些报告涉及6至15周龄婴儿在接种RotaTeq（RV5）或Rotarix（RV1）疫苗并同时接种沛儿（PCV7）或沛儿13（PCV13）后0至6天和0至29天内发生的LRTI。在接种RV5或RV1并同时接种任何一种肺炎球菌疫苗后的0至6天和0至29天内，向VAERS报告的LRTI情况没有显著差异。