Sakamoto G
Gan No Rinsho. 1985 May;Suppl:105-13.
The characteristics of histological classification of breast cancer by Stewart F.W., WHO and Japan Mammary Cancer Society (published in 1971 and revised in 1984) are discussed. The classification of JMCS is fundamentally the same as WHO classification with a subclassification of invasive ductal carcinoma. Invasive ductal carcinoma has three subgroups; papillotubular, solid-tubular and scirrhous carcinoma. In these three subgroups, papillotubular carcinoma shows mainly ductal spread, well histologic differentiation, the lowest lymph node metastasis and the best prognosis. Scirrhous carcinoma shows diffuse stromal infiltration, poor histologic differentiation, the highest metastasis and the worst prognosis. Solid-tubular carcinoma with expansive stromal invasion shows intermediate biological behavior. Thus, the JMCS classification contains in itself not only histologic type but also the mode of spread, grade of histologic differentiation, ratio of lymph node metastasis and prognosis.
讨论了斯图尔特·F.W.、世界卫生组织（WHO）以及日本乳腺癌协会（1971年发布，1984年修订）对乳腺癌的组织学分类特征。日本乳腺癌协会（JMCS）的分类与WHO分类基本相同，对浸润性导管癌进行了再分类。浸润性导管癌有三个亚组：乳头管状癌、实体管状癌和硬癌。在这三个亚组中，乳头管状癌主要表现为导管播散，组织学分化良好，淋巴结转移率最低，预后最佳。硬癌表现为弥漫性间质浸润，组织学分化差，转移率最高，预后最差。具有扩张性间质浸润的实体管状癌表现出中等的生物学行为。因此，JMCS分类本身不仅包含组织学类型，还包含播散方式、组织学分化程度、淋巴结转移率和预后。
