Ministry of National Guard Health Affairs, Division of Prosthodontics, Department of Dental Services, Riyadh, Saudi Arabia.
Ministry of National Guard Health Affairs, Division of Advanced Education in General Dentistry, Department of Dental Services, Riyadh, Saudi Arabia.
Braz Oral Res. 2018 Jul 10;32:e57. doi: 10.1590/1807-3107bor-2018.vol32.0057.
To evaluate peri-implant bone loss (PIBL) and stability around submerged and non-submerged dental implants in patients with and without type 2 diabetes mellitus (T2DM). Thirty-five T2DM and non-diabetic (NT2DM) patients were included in this study. Demographic data were recorded using a questionnaire and PIBL was measured on digital radiographs. Resonance frequency analysis (RFA) was carried out for each implant at the time of fixture placement and at 3 months in both groups. P values less than 0.05 were considered statistically significant. One hundred and eighteen dental implants with a mean height of 10 to 12 mm and 3.3 to 4.1 mm in diameter were placed. The comparison of the mean RFA values at baseline and at 3 months was statistically significant (p = 0.008) in T2DM patients. The inter-group mean RFA values at baseline and at 3 months were not significant (p > 0.05). PIBL was significantly high in T2DM as compared to NT2DM patients at each follow-up (p < 0.05). At 2, 3, and 7 years, non-submerged dental implants showed significantly high PIBL in T2DM patients as compared to NT2DM individuals (p<0.05). The results of the present clinical study demonstrate increased PIBL around non-submerged single-tooth implant-supported restorations in T2DM patients, which may be due to the immune inflammatory status.
评估 2 型糖尿病（T2DM）患者和非 2 型糖尿病（NT2DM）患者中，潜入式和非潜入式牙种植体周围的骨损失（PIBL）和稳定性。本研究纳入了 35 名 T2DM 和非糖尿病患者。使用问卷记录人口统计学数据，并在数字射线照片上测量 PIBL。在两组中，在固定器放置时和 3 个月时，对每个植入物进行共振频率分析（RFA）。P 值小于 0.05 被认为具有统计学意义。共植入 118 颗牙种植体，平均高度为 10-12mm，直径为 3.3-4.1mm。T2DM 患者的基线和 3 个月时的平均 RFA 值比较具有统计学意义（p=0.008）。两组的基线和 3 个月时的平均 RFA 值无显著差异（p>0.05）。与 NT2DM 患者相比，T2DM 患者的 PIBL 在每次随访时均显著更高（p<0.05）。在 2、3 和 7 年时，与 NT2DM 个体相比，T2DM 患者的非潜入式牙种植体显示出明显更高的 PIBL（p<0.05）。本临床研究的结果表明，T2DM 患者非潜入式单牙种植体支持修复体周围的 PIBL 增加，这可能是由于免疫炎症状态所致。
