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剖宫产率与产程关系的仿真模型。

Simulation model of the relationship between cesarean section rates and labor duration.

机构信息

Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

Edward P. Fitts Department of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, 27695, USA.

出版信息

Health Care Manag Sci. 2019 Dec;22(4):635-657. doi: 10.1007/s10729-018-9449-3. Epub 2018 Jul 11.

Abstract

Cesarean delivery is the most common major abdominal surgery in many parts of the world, and it accounts for nearly one-third of births in the United States. For a patient who requires a C-section, allowing prolonged labor is not recommended because of the increased risk of infection. However, for a patient who is capable of a successful vaginal delivery, performing an unnecessary C-section can have a substantial adverse impact on the patient's future health. We develop two stochastic simulation models of the delivery process for women in labor; and our objectives are (i) to represent the natural progression of labor and thereby gain insights concerning the duration of labor as it depends on the dilation state for induced, augmented, and spontaneous labors; and (ii) to evaluate the Friedman curve and other labor-progression rules, including their impact on the C-section rate and on the rates of maternal and fetal complications. To use a shifted lognormal distribution for modeling the duration of labor in each dilation state and for each type of labor, we formulate a percentile-matching procedure that requires three estimated quantiles of each distribution as reported in the literature. Based on results generated by both simulation models, we concluded that for singleton births by nulliparous women with no prior complications, labor duration longer than two hours (i.e., the time limit for labor arrest based on the Friedman curve) should be allowed in each dilation state; furthermore, the allowed labor duration should be a function of dilation state.

摘要

剖宫产术是世界上许多地区最常见的大型腹部手术,占美国分娩总数的近三分之一。对于需要剖宫产的患者,不建议延长产程,因为这会增加感染的风险。然而,对于能够成功进行阴道分娩的患者,进行不必要的剖宫产会对患者未来的健康产生重大不利影响。我们为待产妇女开发了两种分娩过程的随机模拟模型;我们的目标是:(i) 代表产程的自然进展,从而深入了解产程的持续时间,因为它取决于诱导、增强和自然分娩的扩张状态;(ii) 评估弗里德曼曲线和其他产程进展规则,包括它们对剖宫产率以及母婴并发症率的影响。为了在每个扩张状态和每种类型的分娩中使用移位对数正态分布来建模产程持续时间,我们制定了一个百分位数匹配程序,该程序需要文献中报告的每个分布的三个估计分位数。基于两个模拟模型生成的结果,我们得出结论,对于无先前并发症的初产妇的单胎分娩,在每个扩张状态下,应允许产程持续时间超过两小时(即基于弗里德曼曲线的产程停止时间限制);此外,允许的产程持续时间应是扩张状态的函数。

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