Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.
Al Faisal University, Riyadh, Kingdom of Saudi Arabia.
Ann Surg. 2020 Mar;271(3):542-548. doi: 10.1097/SLA.0000000000002948.
To evaluate the learning curve of an expert liver transplantation surgeon approaching fully laparoscopic living donor left lateral sectionectomy (L-LLS) under proctorship.
Laparoscopic liver resections necessitate a long learning curve trough a stepwise fulfillment of difficulties. L-LLS requires expertise in both living donor liver transplantation and advanced laparoscopic liver surgery. There is currently no data about the learning curve of L-LLS.
A total of 72 pure L-LLS were included in this study. A Broken line model was used to identify the periods of the learning curve. A CUSUM analysis of the operative time was performed to evaluate improvements of outcomes with time. To evaluate the relationship between operative time and progressive number of procedures, a linear regression model was applied. A receiver operating characteristic (ROC) curve was carried out to identify the cutoff for completion of the learning curve.
Operative time decreased with the progressive increase of procedures. Two cutoffs and 3 different periods were identified: cases 1 to 22, cases 23 to 55, and cases 56 to 72. A significant decrease in blood loss and operative time was noted. The CUSUM analysis showed an increase in operative time in the first period, a stable duration in the second period, and a decrease in the last. Blood loss was significantly associated with an increase in operative time (P = 0.003). According to the ROC curve, the learning curve was completed after 25 procedures.
L-LLS is a safe procedure that can be standardized and successfully taught to surgeons with large experience in donor hepatectomy through a proctored learning curve.
评估在指导下,一位经验丰富的肝移植外科医生在完全腹腔镜下进行活体供体左外叶切除术(L-LLS)的学习曲线。
腹腔镜肝切除术需要通过逐步克服困难来实现长期的学习曲线。L-LLS 需要在活体供肝移植和先进的腹腔镜肝手术方面都有专业知识。目前,关于 L-LLS 的学习曲线尚无数据。
本研究共纳入 72 例纯 L-LLS。采用折线模型确定学习曲线的阶段。通过手术时间的累积和分析(CUSUM)来评估随着时间的推移手术结果的改善情况。为了评估手术时间与手术次数之间的关系,应用线性回归模型。进行受试者工作特征(ROC)曲线分析,以确定学习曲线完成的截止点。
随着手术次数的增加,手术时间逐渐减少。确定了两个截止点和 3 个不同阶段:第 1 至 22 例、第 23 至 55 例和第 56 至 72 例。术中出血量和手术时间显著减少。CUSUM 分析显示,第一阶段手术时间增加,第二阶段稳定,最后阶段减少。术中出血量与手术时间的增加显著相关(P = 0.003)。根据 ROC 曲线,学习曲线在 25 例手术后完成。
L-LLS 是一种安全的手术方法,可以通过有经验的供肝切除术指导,将其标准化并成功教授给外科医生。