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微创供体肝切除术

Minimally Invasive Donor Hepatectomy.

作者信息

Venkatakrishnan Guhan, Nair Krishnanunni, Pillai Thankamony Amma Binoj S, Varghese Christi T, Mallick Shweta, Surendran Sudhindran

机构信息

Department of Gastrointestinal Surgery and Solid Organ Transplantation, Amrita Institute of Medical Sciences and Research Centre, Amrita University, Kochi, Kerala, India.

出版信息

J Clin Exp Hepatol. 2025 Jul-Aug;15(4):102516. doi: 10.1016/j.jceh.2025.102516. Epub 2025 Feb 19.

DOI:10.1016/j.jceh.2025.102516
PMID:40151473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11938047/
Abstract

Minimally invasive donor hepatectomy (MIDH) involves either laparoscopic or robot-assisted technique, with the graft being retrieved through a remote incision. Current evidence reports faster recovery and better quality of life following MIDH than open donor hepatectomy, although these are limited to a handful of high-volume transplant centers. Nonetheless, grafts obtained by MIDH have a slight disadvantage of having shorter vein lengths than its open counterpart. Additionally, biliary complications are more prevalent in recipients of grafts retrieved by laparoscopic technique, while those obtained by the robotic platform demonstrate biliary complication rates comparable to, or even better than, those from open donor hepatectomy. Widespread application of MIDH has still not occurred across the world. This narrative review explores the challenges faced by the transplant surgeons when transitioning from open donor hepatectomy to MIDH, standard technique of robotic donor hepatectomy and suggests strategies to overcome the learning curve. It compares laparoscopic and robotic donor hepatectomies, detailing the advantages and disadvantages of each approach, as well as their outcomes.

摘要

微创供体肝切除术(MIDH)包括腹腔镜或机器人辅助技术,移植物通过远处切口获取。目前的证据表明,与开放性供体肝切除术相比,MIDH术后恢复更快,生活质量更高,尽管这些仅限于少数高容量移植中心。尽管如此,MIDH获取的移植物有一个轻微的缺点,即静脉长度比开放性供体肝切除术获取的移植物短。此外,腹腔镜技术获取的移植物受者发生胆道并发症更为普遍,而机器人平台获取的移植物的胆道并发症发生率与开放性供体肝切除术相当,甚至更好。MIDH在全球范围内仍未广泛应用。这篇叙述性综述探讨了移植外科医生从开放性供体肝切除术过渡到MIDH时面临的挑战、机器人供体肝切除术的标准技术,并提出了克服学习曲线的策略。它比较了腹腔镜和机器人供体肝切除术,详细阐述了每种方法的优缺点及其结果。