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单纯腹腔镜活体供体右半肝切除术的安全性和可行性

Safety and feasibility of pure laparoscopic living donor right hepatectomy.

作者信息

Kim Sang-Hoon, Kim Ki-Hun, Rotellar Fernando, Aliseda Daniel

机构信息

Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.

HPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Pamplona, Spain.

出版信息

Updates Surg. 2024 Oct 15. doi: 10.1007/s13304-024-01920-5.

DOI:10.1007/s13304-024-01920-5
PMID:39407055
Abstract

Pure laparoscopic living-donor right hepatectomy (PLDRH) has emerged as a significant advancement in liver transplantation, offering reduced donor morbidity and improved recovery times. However, PLDRH is still performed in only a limited number of centers. This retrospective study reports on the outcomes of 215 living donors who underwent PLDRH at Asan Medical Center in Seoul, Korea between November 2014 and December 2021. We reviewed donor and recipient demographics and anatomical characteristics of the donor grafts. Donor complications were classified and evaluated based on the Clavien-Dindo classification. The incidence of early donor complications within 30 days of surgery was 0.9% (n = 3), with minor complications in 0.3% (n = 1) patients and major complications in 0.6% (n = 2). No biliary complications were observed and no late complications had been reported by 30 days after surgery. The mean length of postoperative hospital stay was 7.2 days. PLDRH was a safe and feasible surgical technique characterized by a low complication rate and short hospital stays. PLDRH has the potential to become the standard procedure for the retrieval of right liver grafts from living donors.

摘要

纯腹腔镜活体供体右半肝切除术(PLDRH)已成为肝移植领域的一项重大进展,可降低供体发病率并缩短恢复时间。然而,实施PLDRH的中心数量仍然有限。这项回顾性研究报告了2014年11月至2021年12月期间在韩国首尔峨山医学中心接受PLDRH的215名活体供体的手术结果。我们回顾了供体和受体的人口统计学数据以及供体移植物的解剖特征。根据Clavien-Dindo分类法对供体并发症进行分类和评估。术后30天内早期供体并发症的发生率为0.9%(n = 3),其中轻微并发症发生率为0.3%(n = 1),严重并发症发生率为0.6%(n = 2)。未观察到胆系并发症,术后30天内也未报告晚期并发症。术后平均住院时间为7.2天。PLDRH是一种安全可行的手术技术,具有并发症发生率低和住院时间短的特点。PLDRH有可能成为从活体供体获取右肝移植物的标准术式。

相似文献

1
Safety and feasibility of pure laparoscopic living donor right hepatectomy.单纯腹腔镜活体供体右半肝切除术的安全性和可行性
Updates Surg. 2024 Oct 15. doi: 10.1007/s13304-024-01920-5.
2
Pure Laparoscopic Versus Open Right Hepatectomy in Live Liver Donors: A Propensity Score-matched Analysis.纯腹腔镜与开腹右半肝切除术在活体肝供者中的应用:倾向评分匹配分析。
Ann Surg. 2022 Jan 1;275(1):e206-e212. doi: 10.1097/SLA.0000000000003914.
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One Hundred Fifteen Cases of Pure Laparoscopic Living Donor Right Hepatectomy at a Single Center.单中心 115 例纯腹腔镜活体右半肝切除术。
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4
Comparison of perioperative outcomes between pure laparoscopic surgery and open right hepatectomy in living donor hepatectomy: Propensity score matching analysis.活体肝移植中单纯腹腔镜手术与开腹右半肝切除术围手术期结局的比较:倾向评分匹配分析
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Donor body mass index over 30 is no barrier for pure laparoscopic donor right hepatectomy.供体体重指数超过30并非单纯腹腔镜供体右半肝切除术的障碍。
Ann Hepatobiliary Pancreat Surg. 2024 Aug 31;28(3):337-343. doi: 10.14701/ahbps.24-020. Epub 2024 Apr 3.
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Influence of Large Grafts Weighing ≥ 1000 g on Outcome of Pure Laparoscopic Donor Right Hepatectomy.> 重量≥1000g 的大供肝对纯腹腔镜供肝右切除术效果的影响。
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Criteria for selecting living liver donors to optimize recipient outcomes in pure laparoscopic donor right hepatectomy: a cohort study.纯腹腔镜右半肝活体肝移植中选择供体以优化受体结局的标准:一项队列研究。
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Pure laparoscopic living donor hepatectomy: Focus on 55 donors undergoing right hepatectomy.纯腹腔镜活体供肝切除术:关注 55 例右半肝切除术供者。
Am J Transplant. 2018 Feb;18(2):434-443. doi: 10.1111/ajt.14455. Epub 2017 Sep 7.

本文引用的文献

1
Comparing purely laparoscopic versus open living donor right hepatectomy: propensity score-matched analysis.
Br J Surg. 2021 Jul 23;108(7):e233-e234. doi: 10.1093/bjs/znab090.
2
Timing for Introduction of Total Laparoscopic Living Donor Right Hepatectomy; Initial Experience Based on the Data of Laparoscopic Major Hepatectomy.全腹腔镜活体供肝右叶切除术的引入时机;基于腹腔镜肝切除术数据的初步经验。
Transplantation. 2021 Jun 1;105(6):1273-1279. doi: 10.1097/TP.0000000000003344.
3
Comparison of liver regeneration in laparoscopic versus open right hemihepatectomy for adult living donor liver transplantation.腹腔镜与开放右半肝切除术用于成人活体肝移植时肝脏再生情况的比较
Ann Hepatobiliary Pancreat Surg. 2020 Feb;24(1):33-37. doi: 10.14701/ahbps.2020.24.1.33. Epub 2020 Feb 27.
4
Learning curve of laparoscopic living donor right hepatectomy.腹腔镜活体供肝右叶切除术的学习曲线。
Br J Surg. 2020 Feb;107(3):278-288. doi: 10.1002/bjs.11350. Epub 2019 Oct 25.
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Safety and Risk Factors of Pure Laparoscopic Living Donor Right Hepatectomy: Comparison to Open Technique in Propensity Score-matched Analysis.纯腹腔镜活体供肝右叶切除术的安全性和风险因素:倾向评分匹配分析与开放技术比较。
Transplantation. 2019 Oct;103(10):e308-e316. doi: 10.1097/TP.0000000000002834.
6
The learning curve in pure laparoscopic donor right hepatectomy: a cumulative sum analysis.纯腹腔镜供体右半肝切除术的学习曲线:累积和分析。
Surg Endosc. 2019 Nov;33(11):3741-3748. doi: 10.1007/s00464-019-06668-3. Epub 2019 Feb 15.
7
Learning Curve Under Proctorship of Pure Laparoscopic Living Donor Left Lateral Sectionectomy for Pediatric Transplantation.带教下纯腹腔镜活体供体左外侧叶切除术的学习曲线在儿科移植中的应用。
Ann Surg. 2020 Mar;271(3):542-548. doi: 10.1097/SLA.0000000000002948.
8
Initial experience with purely laparoscopic living-donor right hepatectomy.纯腹腔镜活体右半肝切除术的初步经验。
Br J Surg. 2018 May;105(6):751-759. doi: 10.1002/bjs.10777. Epub 2018 Mar 26.
9
Pure laparoscopic living donor hepatectomy: Focus on 55 donors undergoing right hepatectomy.纯腹腔镜活体供肝切除术:关注 55 例右半肝切除术供者。
Am J Transplant. 2018 Feb;18(2):434-443. doi: 10.1111/ajt.14455. Epub 2017 Sep 7.
10
Initial Outcomes of Pure Laparoscopic Living Donor Right Hepatectomy in an Experienced Adult Living Donor Liver Transplant Center.经验丰富的成人活体肝移植中心中纯腹腔镜活体右半肝切除术的初步结果。
Transplantation. 2017 May;101(5):1106-1110. doi: 10.1097/TP.0000000000001637.